Inhibition of OCTN2-mediated transport of carnitine by etoposide (Q36302949)

13 August 2017

Inhibition of OCTN2-mediated transport of carnitine by etoposide (English)

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13 August 2017

8

Alex Sparreboom

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13 August 2017

Sharyn D Baker

7

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ORCID Public Data File 2021

Cynthia L Lancaster

2

object named as

Cynthia S Lancaster

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13 August 2017

Chaoxin Hu

1

1 reference

13 August 2017

Zhili Zuo

3

1 reference

13 August 2017

Shuiying Hu

4

1 reference

13 August 2017

Zhaoyuan Chen

5

1 reference

13 August 2017

Jeffrey E Rubnitz

6

1 reference

13 August 2017

2 March 2012

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Molecular Cancer Therapeutics

13 August 2017

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13 August 2017

11

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13 August 2017

4

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13 August 2017

921-929

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Cisplatin-induced downregulation of OCTN2 affects carnitine wasting

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Novel inhibitors of human organic cation/carnitine transporter (hOCTN2) via computational modeling and in vitro testing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Expression and function of efflux drug transporters in the intestine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

OCTN2-mediated transport of carnitine in isolated Sertoli cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Functional regions of organic cation/carnitine transporter OCTN2 (SLC22A5): roles in carnitine recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Molecular and functional characterization of organic cation/carnitine transporter family in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Carnitine deficiency induced by pivampicillin and pivmecillinam therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Organic cation/carnitine transporter OCTN2 (Slc22a5) is responsible for carnitine transport across apical membranes of small intestinal epithelial cells in mouse.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

The effect of dose on the bioavailability of oral etoposide.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Carnitine reduces testicular damage in rats treated with etoposide in the prepubertal phase.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Species difference in intestinal absorption mechanism of etoposide and digoxin between cynomolgus monkey and rat.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Sertoli cell morphological alterations in albino rats treated with etoposide during prepubertal phase.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Pharmacokinetic comparison of oral and intravenous etoposide in patients treated with the CHOEP-regimen for malignant lymphomas.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Pharmacokinetics of VP16-213 in Lewis lung carcinoma bearing mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466062

Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells

22 September 2018

1 reference

12 December 2020

Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment

1 reference

12 December 2020

Bioavailability of low-dose oral etoposide

1 reference

12 December 2020

Defective urinary carnitine transport in heterozygotes for primary carnitine deficiency

1 reference

12 December 2020

Renal handling of free and acylcarnitine in secondary carnitine deficiency

1 reference

12 December 2020

Valproate treatment and carnitine deficiency

1 reference

12 December 2020

Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance

1 reference

12 December 2020

10.1158/1535-7163.MCT-11-0980

Identifiers

DOI

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13 August 2017

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13 August 2017

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