p73, a sophisticated p53 family member in the cancer world (Q36306728)

13 August 2017

1 reference

title

p73, a sophisticated p53 family member in the cancer world (English)

1 reference

13 August 2017

Toshinori Ozaki

1

1 reference

PubMed ID

16271066

13 August 2017

Akira Nakagawara

series ordinal

2

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13 August 2017

1 November 2005

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13 August 2017

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13 August 2017

96

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13 August 2017

11

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13 August 2017

729-737

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

13 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p53 family genes: structural comparison, expression and mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Induction of neuronal differentiation by p73 in a neuroblastoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73: Friend or foe in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

DeltaNp73beta is active in transactivation and growth suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Role of the p53-homologue p73 in E2F1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Absence of mutation of the p73 gene localized at chromosome 1p36.3 in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

RETRACTED: p73alpha regulation by Chk1 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Protein stability and function of p73 are modulated by a physical interaction with RanBPM in mammalian cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

A link between p73 transcriptional activity and p73 degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

The ubiquitin-protein ligase Itch regulates p73 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

A novel HECT-type E3 ubiquitin ligase, NEDL2, stabilizes p73 and enhances its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

c-Jun regulates the stability and activity of the p53 homologue, p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Identification of protein kinase A catalytic subunit beta as a novel binding partner of p73 and regulation of p73 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

When p53 needs p73 to be functional - forced p73 expression induces nuclear accumulation of endogenous p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73 competes with p53 and attenuates its response in a human ovarian cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Roles for p53 and p73 during oligodendrocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

From p63 to p53 across p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00116.X

10.1111/J.1349-7006.2005.00116.X

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16271066