From p63 to p53 across p73. (Q34164614)

31 July 2017

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title

From p63 to p53 across p73. (English)

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31 July 2017

2

M Rossi

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31 July 2017

G Fontemaggi

3

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Silvia Soddu

object named as

S Soddu

5

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author name string

S Strano

1

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31 July 2017

E Munarriz

4

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31 July 2017

A Sacchi

6

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31 July 2017

G Blandino

7

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31 July 2017

language of work or name

English

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publication date

1 February 2001

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31 July 2017

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31 July 2017

490

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31 July 2017

3

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31 July 2017

163-170

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A novel protein with strong homology to the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A new human p53 homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Structural aspects of the p53 protein in relation to gene evolution: a second look.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Molecular cloning and functional characterization of the upstream promoter region of the human p73 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Lonely no more: p53 finds its kin in a tumor suppressor haven

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 Family members p63 and p73 are SAM domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Predicting functions from protein sequences--where are the bottlenecks?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Regulation and activation of p53 and its family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mdm2 binds p73 alpha without targeting degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

MDM2 and MDMX bind and stabilize the p53-related protein p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

SUMO-1 modification activates the transcriptional response of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Regulation of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

MEKK1/JNK signaling stabilizes and activates p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Regulation of p53 function and stability by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Excess beta-catenin promotes accumulation of transcriptionally active p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The large T antigen of simian virus 40 binds and inactivates p53 but not p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Synergistic activation of transcription by CBP and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Recruitment of p300/CBP in p53-dependent signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Binding and modulation of p53 by p300/CBP coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Interference with p53 protein inhibits hematopoietic and muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The role of wild-type p53 in the differentiation of primary hemopoietic and muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 regulates myogenesis by triggering the differentiation activity of pRb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 activity is essential for normal development in Xenopus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Gain of function mutations in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

The emerging p53 gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Comparative study of the p53-mdm2 and p53-MDMX interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p53 is involved in the differentiation but not in the differentiation-associated apoptosis of myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

P53 gene alterations in human tumors: perspectives for cancer control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Overexpression of the wild type p73 gene in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Negative feedback regulation of wild-type p53 biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

mdm2 expression is induced by wild type p53 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902119-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(01)02119-6

1 reference

31 July 2017

1 reference