Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma (Q36322562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583032%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma (English)

1 reference

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5 January 2020

0 references

1

1 reference

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5 January 2020

Carl R Walkley

9

1 reference

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5 January 2020

David Bowtell

14

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5 January 2020

Gabriel M Gutierrez

16

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5 January 2020

author name string

Sandra A Johnson

2

1 reference

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5 January 2020

Natalie A Sims

3

1 reference

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5 January 2020

Melanie K Trivett

4

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5 January 2020

John L Slavin

5

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5 January 2020

Brian P Rubin

6

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5 January 2020

Paul Waring

7

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5 January 2020

Grant A McArthur

8

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5 January 2020

Andrew J Holloway

10

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5 January 2020

Dileepa Diyagama

11

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5 January 2020

Jonathon E Grim

12

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5 January 2020

Bruce E Clurman

13

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5 January 2020

Jong-Seo Lee

15

1 reference

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5 January 2020

Denise M Piscopo

17

1 reference

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5 January 2020

Shannon A Carty

18

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5 January 2020

Philip W Hinds

19

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5 January 2020

language of work or name

English

0 references

publication date

1 December 2004

1 reference

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5 January 2020

published in

Journal of Cell Biology

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5 January 2020

volume

167

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5 January 2020

issue

5

1 reference

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5 January 2020

page(s)

925-934

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Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6

5 January 2020

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30 September 2017

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Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours

30 September 2017

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Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation

30 September 2017

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CDK inhibitors: positive and negative regulators of G1-phase progression

30 September 2017

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A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

30 September 2017

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Cbfa1 isoforms exert functional differences in osteoblast differentiation

30 September 2017

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

30 September 2017

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Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

30 September 2017

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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

30 September 2017

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Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1.

30 September 2017

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

30 September 2017

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

30 September 2017

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

30 September 2017

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30 September 2017

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High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

30 September 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

30 September 2017

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Establishment and characterization of conditionally immortalized stromal cell lines from a temperature-sensitive T-Ag transgenic mouse

30 September 2017

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Development and characterization of a conditionally transformed adult human osteoblastic cell line

30 September 2017

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30 September 2017

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30 September 2017

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

30 September 2017

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30 September 2017

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30 September 2017

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Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

30 September 2017

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30 September 2017

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30 September 2017

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

30 September 2017

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Replicative senescence: the human fibroblast comes of age.

30 September 2017

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A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

30 September 2017

1 reference

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

30 September 2017

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A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

30 September 2017

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Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development.

29 June 2018

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Osteoblasts are target cells for transformation in c-fos transgenic mice

29 June 2018

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Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma.

29 June 2018

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Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

29 June 2018

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Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.

22 September 2018

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Transcriptional up-regulation of p27(Kip1) during contact-induced growth arrest in vascular endothelial cells

22 September 2018

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The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

22 September 2018

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The cell cycle regulator p27kip1 contributes to growth and differentiation of osteoblasts.

22 September 2018

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p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation.

22 September 2018

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Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells

22 September 2018

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Osteoclast differentiation is associated with transient upregulation of cyclin-dependent kinase inhibitors p21(WAF1/CIP1) and p27(KIP1)

22 September 2018

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12 December 2020

Distinct roles for p53, p27Kip1, and p21Cip1 during tumor development

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12 December 2020

Mammalian collagenase predisposes bone surfaces to osteoclastic resorption

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12 December 2020

p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors

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12 December 2020

Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1083/JCB.200409187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583032%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583032%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference