Treatment with Sildenafil Improves Insulin Sensitivity in Prediabetes: A Randomized, Controlled Trial (Q36339950)

13 August 2017

Treatment with Sildenafil Improves Insulin Sensitivity in Prediabetes: A Randomized, Controlled Trial (English)

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randomized controlled trial

13 August 2017

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Claudia E Ramirez

1

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13 August 2017

Hui Nian

2

1 reference

13 August 2017

Chang Yu

3

1 reference

13 August 2017

Jorge L Gamboa

4

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13 August 2017

James M Luther

5

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13 August 2017

Nancy J Brown

6

1 reference

13 August 2017

Cyndya A Shibao

7

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13 August 2017

language of work or name

English

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publication date

18 November 2015

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The Journal of Clinical Endocrinology and Metabolism

13 August 2017

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13 August 2017

100

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13 August 2017

4533-4540

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13 August 2017

12

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Effect of phosphodiesterase inhibition on insulin resistance in obese individuals

13 August 2017

1 reference

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Dietary sodium restriction decreases insulin secretion without affecting insulin sensitivity in humans

30 September 2017

1 reference

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Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial

30 September 2017

1 reference

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IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030

30 September 2017

1 reference

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Is there clear and convincing evidence of cardiovascular risk with rosiglitazone?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice

30 September 2017

1 reference

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Incidence rates and predictors of diabetes in those with prediabetes: the Strong Heart Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Endogenous nitric oxide contributes to bradykinin-stimulated glucose uptake but attenuates vascular tissue-type plasminogen activator release

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Atrial natriuretic peptide promotes pancreatic islet beta-cell growth and Akt/Foxo1a/cyclin D2 signaling

30 September 2017

1 reference

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Phosphodiesterase 5 inhibition improves beta-cell function in metabolic syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Nitric oxide inhibits, and carbon monoxide activates, islet acid alpha-glucoside hydrolase activities in parallel with glucose-stimulated insulin secretion

30 September 2017

1 reference

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Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to ANP in the pregnant rat.

30 September 2017

1 reference

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Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

30 September 2017

1 reference

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Albuminuria as a marker of the risk of developing type 2 diabetes in non-diabetic Aboriginal Australians

30 September 2017

1 reference

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Insulin stimulates glucose transport via nitric oxide/cyclic GMP pathway in human vascular smooth muscle cells

30 September 2017

1 reference

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Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.

30 September 2017

1 reference

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Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

30 September 2017

1 reference

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Cyclic-3',5'-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney

30 September 2017

1 reference

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Natriuretic factors and nitric oxide suppress plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Role of cGMP in the regulation of the plasminogen system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Sp1 sites mediate activation of the plasminogen activator inhibitor-1 promoter by glucose in vascular smooth muscle cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Glucose clamp technique: a method for quantifying insulin secretion and resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Dose-response characteristics for arginine-stimulated insulin secretion in man and influence of hyperglycemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Effect of nateglinide on the incidence of diabetes and cardiovascular events

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Daily treatment with sildenafil reverses endothelial dysfunction and oxidative stress in an animal model of insulin resistance

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Comparison of soluble thrombomodulin, von Willebrand factor, tPA/PAI-1 complex, and high-sensitivity CRP concentrations in serum, EDTA plasma, citrated plasma, and acidified citrated plasma (Stabilyte) stored at -70 degrees C for 8-11 years

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Use of the albumin/creatinine ratio to detect microalbuminuria: implications of sex and race

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: insights into the signaling pathway

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4667163

Elevated urinary albumin excretion is associated with impaired arterial dilatory capacity in clinically healthy subjects

22 September 2018

1 reference

12 December 2020

Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells

1 reference

12 December 2020

Antigen levels of plasminogen activator inhibitor type 1 in citrated plasma: determination of the contribution of platelets

1 reference

12 December 2020

Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion

1 reference

12 December 2020

Microalbuminuria precedes the development of NIDDM

1 reference

12 December 2020

Compensatory mechanisms influence hemostasis in setting of eNOS deficiency

1 reference

12 December 2020

Quantification of F2-isoprostanes as a biomarker of oxidative stress

1 reference

12 December 2020

Sildenafil citrate diminishes microalbuminuria and the percentage of A1c in male patients with type 2 diabetes

1 reference

12 December 2020

Inorganic nitrite stimulates pancreatic islet blood flow and insulin secretion

1 reference

12 December 2020

Identifiers

DOI

10.1210/JC.2015-3415

1 reference

13 August 2017

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13 August 2017

1 reference