REV7 counteracts DNA double-strand break resection and affects PARP inhibition (Q36351056)

13 August 2017

REV7 counteracts DNA double-strand break resection and affects PARP inhibition (English)

1 reference

13 August 2017

27

Jiri Bartek

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Kees Jalink

23

Kees Jalink

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Bram van den Broek

18

Bram van den Broek

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Guotai Xu

Guotai Xu

1

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Marco Barazas

Marco Barazas

10

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Dik C van Gent

Dik C van Gent

26

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Sven Rottenberg

Sven Rottenberg

30

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Jiřina Bártková

7

Jirina Bartkova

1 reference

13 August 2017

J Ross Chapman

2

1 reference

13 August 2017

Inger Brandsma

3

1 reference

13 August 2017

Jingsong Yuan

4

1 reference

13 August 2017

Martin Mistrik

5

1 reference

13 August 2017

Peter Bouwman

6

1 reference

13 August 2017

Ewa Gogola

8

1 reference

13 August 2017

Daniël Warmerdam

9

1 reference

13 August 2017

Janneke E Jaspers

11

1 reference

13 August 2017

Kenji Watanabe

12

1 reference

13 August 2017

Mark Pieterse

13

1 reference

13 August 2017

Ariena Kersbergen

14

1 reference

13 August 2017

Wendy Sol

15

1 reference

13 August 2017

Patrick H N Celie

16

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13 August 2017

Philip C Schouten

17

1 reference

13 August 2017

Ahmed Salman

19

1 reference

13 August 2017

Marja Nieuwland

20

1 reference

13 August 2017

Iris de Rink

21

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13 August 2017

Jorma de Ronde

22

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13 August 2017

Simon J Boulton

24

1 reference

13 August 2017

Junjie Chen

25

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13 August 2017

Jos Jonkers

28

1 reference

13 August 2017

Piet Borst

29

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13 August 2017

language of work or name

English

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publication date

23 March 2015

1 reference

13 August 2017

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521

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7553

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13 August 2017

541-544

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4671316/fullTextXML

inferred from PubMed Central ID database lookup

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Mechanisms of resistance to therapies targeting BRCA-mutant cancers

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Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset

30 September 2017

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53BP1: pro choice in DNA repair

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53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

30 September 2017

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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

30 September 2017

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REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.

30 September 2017

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Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors

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Structural Basis of Recruitment of DNA Polymerase by Interaction between REV1 and REV7 Proteins

30 September 2017

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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

30 September 2017

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

30 September 2017

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Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

30 September 2017

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Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

30 September 2017

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

30 September 2017

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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

30 September 2017

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Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

30 September 2017

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Induction of linear tracks of DNA double-strand breaks by alpha-particle irradiation of cells

30 September 2017

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DNA polymerase zeta (pol zeta) in higher eukaryotes

30 September 2017

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Human CtIP promotes DNA end resection

30 September 2017

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A dynamic model for replication protein A (RPA) function in DNA processing pathways

30 September 2017

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

30 September 2017

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

30 September 2017

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

30 September 2017

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JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks

30 September 2017

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A high-throughput functional complementation assay for classification of BRCA1 missense variants

29 June 2018

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PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies

22 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25799992

12 December 2020

inferred from PubMed ID database lookup

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

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Crossref

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE14328

1 reference

Dimensions Publication ID

13 August 2017

1005282802

0 references

Fatcat ID

release_r5e4zxywsjdjhewqzyvmd7nmdq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/r5e4zxywsjdjhewqzyvmd7nmdq

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

PubMed publication ID

25799992

1 reference