Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. (Q36354855)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028188%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer (English)

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9 March 2020

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1

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9 March 2020

Lydia W T Cheung

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9 March 2020

Katherine Stemke-Hale

6

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9 March 2020

Turgut Dogruluk

7

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14

Shannon N Westin

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9 March 2020

24

Gordon B Mills

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9 March 2020

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Bryan T Hennessy

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9 March 2020

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Karen H Lu

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9 March 2020

author name string

Jie Li

3

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9 March 2020

Zhenlin Ju

4

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9 March 2020

Shuangxing Yu

5

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9 March 2020

Yiling Lu

8

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9 March 2020

Xiuping Liu

9

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9 March 2020

Chao Gu

10

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Wei Guo

11

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9 March 2020

Steven E Scherer

12

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9 March 2020

Hannah Carter

13

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9 March 2020

Mary D Dyer

15

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9 March 2020

Roeland G W Verhaak

16

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9 March 2020

Fan Zhang

17

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Rachel Karchin

18

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Chang-Gong Liu

19

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9 March 2020

Russell R Broaddus

21

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9 March 2020

Kenneth L Scott

22

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publication date

1 October 2012

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9 March 2020

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9 March 2020

volume

22

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9 March 2020

issue

11

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9 March 2020

page(s)

2120-2129

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Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

9 March 2020

cites work

1 reference

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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

30 September 2017

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ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers

30 September 2017

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Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer

30 September 2017

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An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer

30 September 2017

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma

30 September 2017

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30 September 2017

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30 September 2017

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FTS (fused toes homolog) a novel oncoprotein involved in uterine cervical carcinogenesis and a potential diagnostic marker for cervical cancer

30 September 2017

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30 September 2017

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30 September 2017

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Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

30 September 2017

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Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM).

30 September 2017

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

30 September 2017

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Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set

30 September 2017

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Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migration

30 September 2017

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Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

30 September 2017

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The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas

30 September 2017

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Upregulated INHBA expression may promote cell proliferation and is associated with poor survival in lung adenocarcinoma

30 September 2017

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Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma

30 September 2017

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Derailed endocytosis: an emerging feature of cancer

30 September 2017

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

30 September 2017

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Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation

30 September 2017

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30 September 2017

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Endometrial Glandular Dysplasia with Frequent p53 Gene Mutation: A Genetic Evidence Supporting Its Precancer Nature for Endometrial Serous Carcinoma

30 September 2017

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PIK3CA gene mutations and amplifications in uterine cancers, identified by methods that avoid confounding by PIK3CA pseudogene sequences

30 September 2017

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Ba/F3 cells and their use in kinase drug discovery

30 September 2017

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Exploiting the PI3K/AKT pathway for cancer drug discovery

30 September 2017

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High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

30 September 2017

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Somatic mutations of the protein kinase gene family in human lung cancer

30 September 2017

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RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains

30 September 2017

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Wnt pathway activation: new relations and locations

30 September 2017

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High activin A-expression in human neuroblastoma: suppression of malignant potential and correlation with favourable clinical outcome

30 September 2017

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Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

30 September 2017

1 reference

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Regulation of endometrial adenocarcinoma cell proliferation by Activin-A and its modulation by 17beta-estradiol.

30 September 2017

1 reference

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Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein

30 September 2017

1 reference

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Activins and inhibins in endocrine and other tumors

30 September 2017

1 reference

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Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

30 September 2017

1 reference

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Myeloblastin is a granulocyte colony-stimulating factor-responsive gene conferring factor-independent growth to hematopoietic cells

30 September 2017

1 reference

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Expression of the c-erbB-3/HER-3 and c-erbB-4/HER-4 growth factor receptors and their ligands, neuregulin-1 alpha, neuregulin-1 beta, and betacellulin, in normal endometrium and endometrial cancer.

30 September 2017

1 reference

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Understanding the words of chromatin regulation

30 September 2017

1 reference

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Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis.

29 June 2018

1 reference

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PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-RAS alterations.

22 September 2018

1 reference

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A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

22 September 2018

1 reference

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Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer.

22 September 2018

1 reference

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Expression and function of activin receptors in human endometrial adenocarcinoma cells.

22 September 2018

1 reference

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Abnormalities of the APC/beta-catenin pathway in endometrial cancer

22 September 2018

1 reference

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PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.

22 September 2018

1 reference

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Mutational Analysis of thePTENGene in Endometrial Carcinoma and Hyperplasia

22 September 2018

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12 December 2020

Mutational analysis of the CTNNB1 and APC genes in uterine endometrioid carcinoma

1 reference

12 December 2020

Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression

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12 December 2020

Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas

1 reference

12 December 2020

Mutational analysis of the CTNNB1 (beta-catenin) gene in human endometrial cancer: frequent mutations at codon 34 that cause nuclear accumulation

1 reference

12 December 2020

The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways

1 reference

12 December 2020

Expression of the epidermal growth factor system in endometrioid endometrial cancer

1 reference

12 December 2020

PIK3CA mutations in the kinase domain (exon 20) of uterine endometrial adenocarcinomas are associated with adverse prognostic parameters

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.137596.112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028188%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028188%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028188%20AND%20SRC:MED&resulttype=core&format=json