The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity (Q36359414)

13 August 2017

The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity (English)

1 reference

13 August 2017

1 reference

GOA release 2020-03-11

Crumbs Dmel_CG6383

1 reference

alternative mRNA splicing, via spliceosome

GOA release 2020-03-11

1 reference

Athea Vichas

1

1 reference

13 August 2017

Matthew T Laurie

series ordinal

2

1 reference

13 August 2017

Jennifer A Zallen

series ordinal

3

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 December 2015

1 reference

13 August 2017

Journal of Cell Biology

1 reference

13 August 2017

211

1 reference

13 August 2017

5

1 reference

13 August 2017

1011-1024

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4674277/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Regulation of alternative splicing in Drosophila by 56 RNA binding proteins

30 September 2017

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The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline

30 September 2017

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30 September 2017

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Context-dependent control of alternative splicing by RNA-binding proteins

30 September 2017

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Diversity and dynamics of the Drosophila transcriptome

30 September 2017

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30 September 2017

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Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8

30 September 2017

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Genes and mutations causing retinitis pigmentosa

30 September 2017

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Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity

30 September 2017

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RNA helicases in splicing

30 September 2017

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Differential analysis of gene regulation at transcript resolution with RNA-seq

30 September 2017

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Anisotropy of Crumbs and aPKC drives myosin cable assembly during tube formation

30 September 2017

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Cadherin junctions and their cytoskeleton(s).

30 September 2017

1 reference

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Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome

30 September 2017

1 reference

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Cortical dynein is critical for proper spindle positioning in human cells

30 September 2017

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Ski2-like RNA helicase structures: common themes and complex assemblies

30 September 2017

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The apical polarity protein network in Drosophila epithelial cells: regulation of polarity, junctions, morphogenesis, cell growth, and survival

30 September 2017

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Differential positioning of adherens junctions is associated with initiation of epithelial folding

30 September 2017

1 reference

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The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome

30 September 2017

1 reference

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A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization

30 September 2017

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CRB1 mutations in inherited retinal dystrophies

30 September 2017

1 reference

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Functional consequences of developmentally regulated alternative splicing

30 September 2017

1 reference

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Oscillatory behaviors and hierarchical assembly of contractile structures in intercalating cells

30 September 2017

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RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation

30 September 2017

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The developmental transcriptome of Drosophila melanogaster

30 September 2017

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Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia

30 September 2017

1 reference

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Adherens junctions: from molecules to morphogenesis

30 September 2017

1 reference

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aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

30 September 2017

1 reference

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Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs

30 September 2017

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The Crumbs complex: from epithelial-cell polarity to retinal degeneration

30 September 2017

1 reference

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Junctional trafficking and epithelial morphogenesis

30 September 2017

1 reference

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Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration

30 September 2017

1 reference

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Unlocking the secrets of the genome

30 September 2017

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PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts

30 September 2017

1 reference

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Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2

30 September 2017

1 reference

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Independent cadherin-catenin and Bazooka clusters interact to assemble adherens junctions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Alternative splicing and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Alternative isoform regulation in human tissue transcriptomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Tissue-specific splicing factor gene expression signatures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Analyzing real-time PCR data by the comparative C(T) method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Microtubule-induced cortical cell polarity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Identification of alternative splicing regulators by RNA interference in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Pre-mRNA splicing and human disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of Ep-CAM molecules in homophilic adhesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Isolation and mapping of novel candidate genes for retinal disorders using suppression subtractive hybridization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

A spatial and temporal map of C. elegans gene expression

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Microtubule arrays present during the syncytial and cellular blastoderm stages of the early Drosophila embryo.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Principles of E-cadherin supramolecular organization in vivo.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Sticking together the Crumbs - an unexpected function for an old friend

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

A functional role of the extracellular domain of Crumbs in cell architecture and apicobasal polarity.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Crumbs/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

A two-tiered mechanism for stabilization and immobilization of E-cadherin.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Multicellular rosette formation links planar cell polarity to tissue morphogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Patterned gene expression directs bipolar planar polarity in Drosophila

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Integrated activity of PDZ protein complexes regulates epithelial polarity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Dynein binds to beta-catenin and may tether microtubules at adherens junctions.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Crumbs, a component of the apical membrane, is required for zonula adherens formation in primary epithelia of Drosophila.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

The development of cellular junctions in the Drosophila embryo

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4674277

HIF1A signaling selectively supports proliferation of breast cancer in the brain

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201504083

Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26644515

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Function of alternative splicing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26644515

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201504083

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

26644515

1 reference