CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. (Q36369627)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602635%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation (English)

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12 November 2019

4

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12 November 2019

author name string

P D Holler

1

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12 November 2019

A R Lim

2

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12 November 2019

B K Cho

3

1 reference

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12 November 2019

D M Kranz

5

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12 November 2019

language of work or name

English

0 references

publication date

1 October 2001

1 reference

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Journal of Experimental Medicine

12 November 2019

published in

1 reference

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12 November 2019

volume

194

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12 November 2019

issue

8

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12 November 2019

page(s)

1043-1052

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The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity

12 November 2019

cites work

1 reference

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30 September 2017

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30 September 2017

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T cell receptor-MHC interactions up close

30 September 2017

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30 September 2017

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Breaking the affinity ceiling for antibodies and T cell receptors

30 September 2017

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30 September 2017

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30 September 2017

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Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

30 September 2017

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30 September 2017

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Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.

30 September 2017

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Deficient cellular immunity--finding and fixing the defects

30 September 2017

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The immunological synapse: a molecular machine controlling T cell activation

30 September 2017

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Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

30 September 2017

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Three-dimensional segregation of supramolecular activation clusters in T cells

30 September 2017

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Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

30 September 2017

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Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization

30 September 2017

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Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors

30 September 2017

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Kinetic discrimination in T-cell activation

30 September 2017

1 reference

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T-cell-receptor affinity and thymocyte positive selection

30 September 2017

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The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes

30 September 2017

1 reference

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High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins

30 September 2017

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

30 September 2017

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Kinetic proofreading in T-cell receptor signal transduction

30 September 2017

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Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.

30 September 2017

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Serial triggering of many T-cell receptors by a few peptide-MHC complexes

30 September 2017

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Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

30 September 2017

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Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.

30 September 2017

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Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells

28 June 2018

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A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

28 June 2018

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Differential transport requirements of HLA and H-2 class I glycoproteins

28 June 2018

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Ligand recognition by alpha beta T cell receptors

28 June 2018

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Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

21 January 2018

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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

21 January 2018

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A kinetic window constricts the T cell receptor repertoire in the thymus.

21 January 2018

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Ligand-specific oligomerization of T-cell receptor molecules

21 January 2018

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21 January 2018

Les liaisons dangereuses

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Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin

21 January 2018

1 reference

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Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.194.8.1043

A residue in the center of peptide QL9 affects binding to both Ld and the T cell receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11602635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.194.8.1043

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602635%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602635%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

PubMed publication ID

11602635

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602635%20AND%20SRC:MED&resulttype=core&format=json