Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both? (Q36374629)

13 August 2017

1 reference

title

Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both? (English)

1 reference

13 August 2017

Yanlin Wang

1

1 reference

PubMed ID

16428315

13 August 2017

Robert A Casero

series ordinal

2

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13 August 2017

1 January 2006

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13 August 2017

Journal of Biochemistry

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13 August 2017

139

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13 August 2017

1

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13 August 2017

17-25

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Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin

13 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Polyamines and cancer: old molecules, new understanding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Purification and characterization of spermidine/spermine N1-acetyltransferase from rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Structure of the human spermidine/spermine N1-acetyltransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of alternatively spliced spermidine/spermine N1-acetyltransferase mRNA in the human kidney cells infected by venezuelan equine encephalitis and tick-borne encephalitis viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of a SSAT isoform in response to hypoxia or iron deficiency and its protective effects on cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Nucleotide sequence of hamster spermidine/spermine-N1-acetyltransferase cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Cloning and sequence analysis of the gene and cDNA encoding mouse spermidine/spermine N1-acetyltransferase--a gene uniquely regulated by polyamines and their analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Apoptotic Response to 5-Fluorouracil Treatment Is Mediated by Reduced Polyamines, Non-Autocrine Fas Ligand and Induced Tumor Necrosis Factor Receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Differential transcription of the human spermidine/spermine N1-acetyltransferase (SSAT) gene in human lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

The identification of a cis-element and a trans-acting factor involved in the response to polyamines and polyamine analogues in the regulation of the human spermidine/spermine N1-acetyltransferase gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Post-transcriptional regulation of the content of spermidine/spermine N1-acetyltransferase by N1N12-bis(ethyl)spermine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Structure and critical residues at the active site of spermidine/spermine-N1-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Spermidine/spermine N1-acetyl transferase activity in rat brain following transient focal cerebral ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Genetic approaches to the cellular functions of polyamines in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

21 January 2018

Catabolism of polyamines

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

The role of polyamine catabolism in polyamine analogue-induced programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Inhibition of murine N1-acetylated polyamine oxidase by an acetylenic amine and the allenic amine, MDL 72527.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Mouse spermine oxidase: a model of the catalytic cycle and its inhibition by N,N1-bis(2,3-butadienyl)-1,4-butanediamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Properties of purified recombinant human polyamine oxidase, PAOh1/SMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Maize polyamine oxidase: primary structure from protein and cDNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Heterologous expression and characterization of mouse spermine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase mu isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Direct oxidative DNA damage, apoptosis and radio sensitivity by spermine oxidase activities in mouse neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVJ021

21 January 2018

Identifiers

DOI

10.1093/JB/MVJ021

1 reference

13 August 2017

1 reference

PubMed ID

16428315