c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation (Q36376229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11157052%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11157052%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

0 references

6

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3 November 2019

author name string

K Sabapathy

1

1 reference

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3 November 2019

T Kallunki

2

1 reference

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3 November 2019

J P David

3

1 reference

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3 November 2019

I Graef

4

1 reference

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3 November 2019

M Karin

5

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3 November 2019

language of work or name

English

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publication date

1 February 2001

1 reference

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Journal of Experimental Medicine

3 November 2019

published in

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3 November 2019

volume

193

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3 November 2019

issue

3

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3 November 2019

page(s)

317-328

1 reference

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JNK is required for effector T-cell function but not for T-cell activation

3 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Requirement for transcription factor NFAT in interleukin-2 expression

30 September 2017

1 reference

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Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

The transcription factor NFAT4 is involved in the generation and survival of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.

30 September 2017

1 reference

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AP-1 function and regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Selective interaction of JNK protein kinase isoforms with transcription factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Contingent genetic regulatory events in T lymphocyte activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Nuclear factor of activated T cells contains Fos and Jun.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Transactivation by AP-1 is a molecular target of T cell clonal anergy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

JNK is involved in signal integration during costimulation of T lymphocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

c-Jun is essential for normal mouse development and hepatogenesis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195924

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

5 December 2018

1 reference

12 December 2020

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells

1 reference

12 December 2020

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

12 December 2020

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

1 reference

12 December 2020

Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection

1 reference

12 December 2020

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

12 December 2020

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.193.3.317

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11157052%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11157052%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

11157052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11157052%20AND%20SRC:MED&resulttype=core&format=json