A review of erlotinib and its clinical use. (Q36376408)

13 August 2017

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title

A review of erlotinib and its clinical use. (English)

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13 August 2017

Ming-Sound Tsao

2

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author name string

Patricia A Tang

series ordinal

1

1 reference

PubMed ID

16433583

13 August 2017

Malcolm J Moore

series ordinal

3

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PubMed ID

16433583

13 August 2017

language of work or name

English

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publication date

1 February 2006

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Expert Opinion on Pharmacotherapy

13 August 2017

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13 August 2017

7

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13 August 2017

2

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13 August 2017

177-193

1 reference

Cell signaling by receptor tyrosine kinases

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1 reference

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

21 January 2018

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Prognostic applications of the epidermal growth factor receptor and its ligand, transforming growth factor-alpha.

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21 January 2018

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Studies leading to the identification of ZD1839 (IRESSA): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

21 January 2018

1 reference

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21 January 2018

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Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies

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Randomized cross-over evaluation of body-surface area-based dosing versus flat-fixed dosing of paclitaxel

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Phase I trial of irinotecan, infusional 5-fluorouracil, and leucovorin (FOLFIRI) with erlotinib (OSI-774): early termination due to increased toxicities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

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21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lun

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1 reference

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Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors.

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1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

Determinants of tumor response and survival with erlotinib in patients with non--small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

Erlotinib in previously treated non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer.

21 January 2018

1 reference

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FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets

21 January 2018

1 reference

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Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

21 January 2018

1 reference

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Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

21 January 2018

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Erlotinib in lung cancer - molecular and clinical predictors of outcome

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Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

21 January 2018

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Uncommon presentations of Hodgkin's disease. Case 3. Hodgkin's disease: rectal presentation

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.7.2.177

A phase II trial of ZD1839 (Iressa) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer

21 January 2018

1 reference

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Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.7.2.177

Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck

21 January 2018

1 reference

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Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.

21 January 2018

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Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results

21 January 2018

1 reference

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Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: results from a phase II multicenter study

21 January 2018

1 reference

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Practical management of patients with non-small-cell lung cancer treated with gefitinib

21 January 2018

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Severe acute interstitial pneumonia and gefitinib

21 January 2018

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Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

21 January 2018

1 reference

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Current perspectives on HER2 testing: a review of national testing guidelines

21 January 2018

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

21 January 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

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Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study

21 January 2018

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Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

21 January 2018

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EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

21 January 2018

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High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan

21 January 2018

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Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

21 January 2018

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Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

21 January 2018

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Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

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Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)

21 January 2018

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21 January 2018

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Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730).

21 January 2018

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Toward customized trastuzumab in HER-2/neu-overexpressing non-small-cell lung cancers.

21 January 2018

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Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer

21 January 2018

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Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II Trial

21 January 2018

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21 January 2018

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Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

21 January 2018

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Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study

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21 January 2018

Identifiers

DOI

10.1517/14656566.7.2.177

1 reference

13 August 2017

1 reference

PubMed ID

16433583