Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase (Q36377312)

13 August 2017

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase (English)

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13 August 2017

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14

Jerrold M Olefsky

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13 August 2017

Saswata Talukdar

1

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13 August 2017

Da Young Oh

2

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13 August 2017

Gautam Bandyopadhyay

3

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13 August 2017

Dongmei Li

4

1 reference

13 August 2017

Jianfeng Xu

5

1 reference

13 August 2017

Joanne McNelis

6

1 reference

13 August 2017

Min Lu

7

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13 August 2017

Pingping Li

8

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13 August 2017

Qingyun Yan

9

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13 August 2017

Yimin Zhu

10

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13 August 2017

Jachelle Ofrecio

11

1 reference

13 August 2017

Michael Lin

12

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13 August 2017

Martin B Brenner

13

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13 August 2017

language of work or name

English

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publication date

1 September 2012

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13 August 2017

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13 August 2017

18

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13 August 2017

9

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13 August 2017

1407-1412

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Neutrophils in the activation and regulation of innate and adaptive immunity

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Inflammatory mechanisms in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophils, from marrow to microbes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

The paradox of tumor-associated neutrophils: fueling tumor growth with cytotoxic substances

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Macrophages, inflammation, and insulin resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Normalization of obesity-associated insulin resistance through immunotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophil serine proteases: specific regulators of inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophil elastase: mediator of extracellular matrix destruction and accumulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophils and immunity: challenges and opportunities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

The mechanism mediating the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491143

Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4.

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2885

inferred from DOI database lookup

7 January 2021

based on heuristic

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2885

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM.2885

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

22863787

1 reference