Nitric oxide and MPP+-induced hydroxyl radical generation (Q36389388)

13 August 2017

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title

Nitric oxide and MPP+-induced hydroxyl radical generation (English)

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13 August 2017

T Obata

1

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13 August 2017

language of work or name

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6 February 2006

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Journal of Neural Transmission

13 August 2017

published in

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13 August 2017

volume

113

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13 August 2017

issue

9

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13 August 2017

page(s)

1131-1144

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[11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold

13 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00702-005-0415-0

[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression

21 January 2018

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Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases

21 January 2018

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The structural mimicry of membrane sterols by tamoxifen: evidence from cholesterol coefficients and molecular-modelling for its action as a membrane anti-oxidant and an anti-cancer agent

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00702-005-0415-0

Enhancement by tamoxifen of the membrane antioxidant action of the yeast membrane sterol ergosterol: relevance to the antiyeast and anticancer action of tamoxifen

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00702-005-0415-0

Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-005-0415-0

Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen

21 January 2018

1 reference

12 December 2020

S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity

1 reference

12 December 2020

Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note

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12 December 2020

Aorta and Skeletal Muscle NO Synthase Expression in Experimental Heart Failure

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12 December 2020

Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease.

1 reference

12 December 2020

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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12 December 2020

Vascular endothelial cells synthesize nitric oxide from L-arginine

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12 December 2020

Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants

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12 December 2020

Use of salicylate as a probe for .OH formation in isolated ischemic rat hearts

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12 December 2020

Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum

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12 December 2020

Inhibition of depolarization-induced nitric oxide synthase activation by NS-7, a phenylpyrimidine derivative, in primary neuronal culture

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12 December 2020

The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases

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12 December 2020

In vivo trapping of hydroxyl free radicals in the striatum utilizing intracranial microdialysis perfusion of salicylate: effects of MPTP, MPDP+, and MPP+

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12 December 2020

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures.

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12 December 2020

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1 reference

12 December 2020

Methamphetamine-induced rapid and reversible reduction in the activities of tryptophan hydroxylase and dopamine transporters: oxidative consequences?

1 reference

12 December 2020

Nitric oxide and oxygen radicals: a question of balance

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12 December 2020

Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress.

1 reference

12 December 2020

Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons.

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12 December 2020

Histochemical detection of apoptosis in Parkinson's disease.

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12 December 2020

Hydroxyl radicals and nitric oxide in neurotoxicity and neuroprotection

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12 December 2020

VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity

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12 December 2020

Reserpine prevents hydroxyl radical formation by MPP+ in rat striatum

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12 December 2020

Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions

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12 December 2020

Potassium chloride depolarization enhances MPP+-induced hydroxyl radical generation in the rat striatum

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12 December 2020

Estrogen modulates responses of striatal dopamine neurons to MPP(+): evaluations using in vitro and in vivo techniques

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12 December 2020

Enzyme-independent formation of nitric oxide in biological tissues

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12 December 2020

Inhibition of monoamine oxidase contributes to the protective effect of 7-nitroindazole against MPTP neurotoxicity.

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12 December 2020

Acute effects of 1-methyl-4-phenylpyridinium ion (MPP+) on dopamine and serotonin metabolism in rat striatum as assayed in vivo by a micro-dialysis technique

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12 December 2020

Protective effect of tamoxifen on 1-methyl-4-phenylpyridine-induced hydroxyl radical generation in the rat striatum

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12 December 2020

Methamphetamine- and 1-methyl-4-phenyl- 1,2,3, 6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice

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12 December 2020

The role of nitric oxide in neurodegeneration. Potential for pharmacological intervention

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12 December 2020

Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide

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12 December 2020

Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease

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12 December 2020

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

1 reference

12 December 2020

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

12 December 2020

Estrogen protects primary cortical neurons from glutamate toxicity

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12 December 2020

S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo

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12 December 2020

The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra

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12 December 2020

In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia.

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12 December 2020

Prostaglandins and the release of the adrenergic transmitter

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12 December 2020

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

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12 December 2020

Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum

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12 December 2020

Suppression of hydroxyl radical formation by MAO inhibitors: a novel possible neuroprotective mechanism in dopaminergic neurotoxicity.

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12 December 2020

Blockade by NS-7, a neuroprotective compound, of both L-type and P/Q-type Ca2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture

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12 December 2020

Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.

1 reference

12 December 2020

Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids, and oxidant stress

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12 December 2020

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

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12 December 2020

Dopamine turnover and glutathione oxidation: implications for Parkinson disease

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12 December 2020

MPTP toxicity: implications for research in Parkinson's disease

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12 December 2020

Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport

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12 December 2020

MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis

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12 December 2020

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

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12 December 2020

Rapid and differential losses of in vivo dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) radioligand binding in MPTP-treated mice

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12 December 2020

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase

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12 December 2020

Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism.

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon.

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12 December 2020

Nitric oxide synthase in cardiac sarcoplasmic reticulum

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12 December 2020

The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

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12 December 2020

Oxygen radicals diminish dopamine transporter function in rat striatum

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12 December 2020

Impairment of the neuronal dopamine transporter activity in MPP(+)-treated rat was not prevented by treatments with nitric oxide synthase or poly(ADP-ribose) polymerase inhibitors

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12 December 2020

Effects of MPP+ on the release of serotonin and 5-hydroxyindoleacetic acid from rat striatum in vivo.

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12 December 2020

Determination of hydroxylated aromatic compounds produced via superoxide-dependent formation of hydroxyl radicals by liquid chromatography/electrochemistry

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12 December 2020

The dopamine transporter: a crucial component regulating dopamine transmission.

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12 December 2020

Involvement of oxygen-based radicals in methamphetamine-induced neurotoxicity: evidence from the use of CuZnSOD transgenic mice

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12 December 2020

MPTP neurotoxicity: an overview and characterization of phases of toxicity

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12 December 2020

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

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12 December 2020

Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP.

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12 December 2020

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

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12 December 2020

Structure and function of the dopamine transporter

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12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

12 December 2020

Neurochemical findings in the MPTP model of Parkinson's disease

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12 December 2020

A brainstem atlas of catecholaminergic neurons in man, using melanin as a natural marker

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12 December 2020

Possible mechanism for the neuroprotective effects of L-carnitine on methamphetamine-evoked neurotoxicity

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12 December 2020

In vivo autoxidation of dopamine in guinea pig striatum increases with age.

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12 December 2020

Long-lasting effects of chronic neonatal blockade of N-methyl-D-aspartate receptor through the competitive antagonist CGP 39551 in rats.

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12 December 2020

Etiology and pathogenesis of Parkinson's disease

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12 December 2020

ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production

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12 December 2020

Selective estrogen receptor modulators: structure, function, and clinical use.

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12 December 2020

Protein nitration in Parkinson's disease

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12 December 2020

Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation

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12 December 2020

Nitric oxide and depolarization induce hydroxyl radical generation

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12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

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12 December 2020

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

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12 December 2020

Dopamine efflux by MPTP and hydroxyl radical generation

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12 December 2020

Nitric oxide, mitochondria and neurological disease

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12 December 2020

Oxygen free radical involvement in ischemia and reperfusion injury to brain

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12 December 2020

Molecular physiology and regulation of catecholamine transporters.

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12 December 2020

1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra

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12 December 2020

Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations.

1 reference

12 December 2020

Mechanisms of MPTP toxicity

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12 December 2020

Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease

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12 December 2020

Malfunction of vascular control in lifestyle-related diseases: formation of systemic hemoglobin-nitric oxide complex (HbNO) from dietary nitrite

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12 December 2020

Analysis of the neuroprotective effects of various nitric oxide donor compounds in murine mixed cortical cell culture

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12 December 2020

Parkinson's disease: pathophysiology

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12 December 2020

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

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12 December 2020

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

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12 December 2020

Environmental estrogen-like chemicals and hydroxyl radicals induced by MPTP in the striatum: a review

1 reference

12 December 2020

Calcium overload enhances hydroxyl radical generation by 1-methyl-4 phenylpyridinium ion (MPP+) in rat striatum

1 reference

12 December 2020

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

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12 December 2020

The effect of melanin on iron associated decomposition of hydrogen peroxide

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12 December 2020

Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products.

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12 December 2020

Peroxynitrite and drug-dependent toxicity

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12 December 2020

Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum

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12 December 2020

Altered brain metabolism of iron as a cause of neurodegenerative diseases?

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12 December 2020

Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide

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12 December 2020

Systemic administration of D-amphetamine induced a delayed production of nitric oxide in the striatum of rats

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12 December 2020

[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy

1 reference

12 December 2020

Neurochemical and neurogenetic correlates of Parkinson's disease.

1 reference

12 December 2020

Catecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson's disease

1 reference

12 December 2020

Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology.

1 reference

12 December 2020

Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model.

1 reference

12 December 2020

Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase

1 reference

12 December 2020

Role of nitric oxide in methamphetamine neurotoxicity: protection by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase

1 reference

12 December 2020

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

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12 December 2020

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

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12 December 2020

Evidence of neuronal oxidative damage in Alzheimer's disease.

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12 December 2020

Neuroprotection by nitric oxide against hydroxyl radical-induced nigral neurotoxicity

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12 December 2020

10.1007/S00702-005-0415-0

Identifiers

DOI

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13 August 2017

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