Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low. (Q36392003)

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English	Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.	scientific article

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17 February 2020

Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low (English)

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17 February 2020

type 2 diabetes

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Mediterranean diet

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José María Ordovás

17

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17 February 2020

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17 February 2020

Miguel Ángel Martínez-González

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17 February 2020

Jordi Salas-Salvadó

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17 February 2020

Lluís Serra Majem

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17 February 2020

Miguel-Angel Muñoz

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17 February 2020

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17 February 2020

María-Isabel Covas

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Maria-Isabel Covas

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17 February 2020

Carolina Ortega-Azorín

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Carolina Ortega-Azorín

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17 February 2020

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Eva M Asensio

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17 February 2020

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Oscar Coltell

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17 February 2020

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Fernando Arós

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17 February 2020

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José Lapetra

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17 February 2020

Enrique Gómez-Gracia

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Enrique Gómez-Gracia

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17 February 2020

Miquel Àngel Fiol

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Miquel Fiol

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17 February 2020

Guillermo Sáez-Tormo

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Guillermo Sáez-Tormo

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17 February 2020

Dolores Corella Piquer

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Dolores Corella

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17 February 2020

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Ramon Estruch

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17 February 2020

Xavier Pintó

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17 February 2020

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6 November 2012

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17 February 2020

Cardiovascular Diabetology

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17 February 2020

11

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17 February 2020

137

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17 February 2020

A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

1 reference

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30 September 2017

Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

The diet of diabetic patients in Spain in 2008-2010: accordance with the main dietary recommendations--a cross-sectional study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Effect of folic acid supplementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Obesity and eating behaviour in children and adolescents: contribution of common gene polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Expression of fourteen novel obesity-related genes in Zucker diabetic fatty rats

1 reference

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30 September 2017

Uncoupling protein 2 gene polymorphisms are associated with obesity

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30 September 2017

European genetic variants associated with type 2 diabetes in North African Arabs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Association of FTO polymorphisms with early age of obesity in obese Italian subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Global DNA methylation is associated with insulin resistance: a monozygotic twin study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Mediterranean diet and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study: the InterAct project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

The role of diet in the prevention of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

FTO gene polymorphisms and obesity risk: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

A common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Diet-quality scores and the risk of type 2 diabetes in men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Cohort profile: design and methods of the PREDIMED study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Overexpression of Fto leads to increased food intake and results in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Life course variations in the associations between FTO and MC4R gene variants and body size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Prognostic significance of FTO genotype in the development of obesity in Japanese: the J-SHIPP study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

FTO variants are associated with obesity in the Chinese and Malay populations in Singapore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Common variants near MC4R are associated with fat mass, weight and risk of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

30 September 2017

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

28 June 2018

Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

The rs7204609 polymorphism in the fat mass and obesity-associated gene is positively associated with central obesity and microalbuminuria in patients with type 2 diabetes from Southern Brazil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Combined effects of FTO rs9939609 and MC4R rs17782313 on obesity and BMI in Chinese Han populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

High-fat diet leads to a decreased methylation of the Mc4r gene in the obese BFMI and the lean B6 mouse lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Dietary patterns and nutritional adequacy in a Mediterranean country.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Knockout studies defining different roles for melanocortin receptors in energy homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

21 September 2018

Validation of the Minnesota Leisure Time Physical Activity Questionnaire in Spanish Women

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Meta-analysis Added Power to Identify Variants in FTO Associated With Type 2 Diabetes and Obesity in the Asian Population

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Common variants of FTO and the risk of obesity and type 2 diabetes in Indians

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Relative validity of a semi-quantitative food-frequency questionnaire in an elderly Mediterranean population of Spain

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Associations of Variants inFTOand NearMC4RWith Obesity Traits in South Asian Indians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495759

5 December 2018

Adherence to a Mediterranean-type diet and reduced prevalence of clustered cardiovascular risk factors in a cohort of 3204 high-risk patients

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-11-137

21 January 2018

Is FTO a type 2 diabetes susceptibility gene?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23130628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β2-Adrenergic Receptor Thr164Ile Polymorphism, Obesity, and Diabetes: Comparison with FTO, MC4R, and TMEM18 Polymorphisms in More Than 64,000 Individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/23130628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis and classification of diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23130628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FTO polymorphisms are associated with obesity but not with diabetes in East Asian populations: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23130628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2840-11-137

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23130628%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23130628%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23130628%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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