Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution (Q36392470)

13 August 2017

Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution (English)

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chronic lymphocytic leukemia

13 August 2017

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inferred from title

whole genome sequencing

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15

G Getz

1 reference

13 August 2017

12

S Gabriel

1 reference

13 August 2017

13

E S Lander

1 reference

13 August 2017

S Kasar

1

1 reference

13 August 2017

J Kim

2

1 reference

13 August 2017

R Improgo

3

1 reference

13 August 2017

G Tiao

4

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13 August 2017

P Polak

5

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13 August 2017

N Haradhvala

6

1 reference

13 August 2017

M S Lawrence

7

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13 August 2017

A Kiezun

8

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13 August 2017

S M Fernandes

9

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13 August 2017

S Bahl

10

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13 August 2017

C Sougnez

11

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13 August 2017

H T Kim

14

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13 August 2017

J R Brown

16

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13 August 2017

language of work or name

English

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publication date

7 December 2015

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13 August 2017

Nature Communications

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13 August 2017

6

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13 August 2017

8866

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Creative Commons Attribution 4.0 International

13 August 2017

start time

1 December 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/ncomms9866

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Regulation of AID, the B-cell genome mutator

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Regulation of Aicda expression and AID activity

30 September 2017

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Recurrent targets of aberrant somatic hypermutation in lymphoma

30 September 2017

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Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

30 September 2017

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IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions

30 September 2017

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Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway

30 September 2017

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Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia

30 September 2017

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Mutational processes molding the genomes of 21 breast cancers

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Complex regulation and function of activation-induced cytidine deaminase

30 September 2017

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30 September 2017

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Novel insights into the biology of CLL.

30 September 2017

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30 September 2017

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30 September 2017

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Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

30 September 2017

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30 September 2017

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30 September 2017

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Uracil in DNA and its processing by different DNA glycosylases

30 September 2017

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Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase

30 September 2017

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

30 September 2017

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Molecular mechanisms of antibody somatic hypermutation.

30 September 2017

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30 September 2017

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In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

30 September 2017

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Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

30 September 2017

1 reference

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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

30 September 2017

1 reference

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DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

30 September 2017

1 reference

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Genomic aberrations and survival in chronic lymphocytic leukemia

30 September 2017

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30 September 2017

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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

30 September 2017

1 reference

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Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

30 September 2017

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APOBEC3 signature mutations in chronic lymphocytic leukemia

30 September 2017

1 reference

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Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions

28 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686820

Frequency of 5'IGH deletions in B-cell chronic lymphocytic leukemia.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686820

High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686820

The pattern and distribution of immunoglobulin VH gene mutations in chronic lymphocytic leukemia B cells are consistent with the canonical somatic hypermutation process.

21 September 2018

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Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone.

21 September 2018

1 reference

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High prevalence of somatic MAP2K1 mutations in BRAF V600E-negative Langerhans cell histiocytosis.

21 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS9866

Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26638776

12 December 2020

inferred from PubMed ID database lookup

Biological and clinical characterization of recurrent 14q deletions in CLL and other mature B-cell neoplasms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26638776

12 December 2020

inferred from PubMed ID database lookup

Independent coexistence of clones with 13q14 deletion at reciprocal translocation breakpoint and 13q14 interstitial deletion in chronic lymphocytic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26638776

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS9866

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference