Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes (Q36393112)

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English	Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes (English)

1 reference

Europe PubMed Central

13 August 2017

type 2 diabetes

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author name string

Rosalyn D Ferguson

1

1 reference

Europe PubMed Central

13 August 2017

Ruslan Novosyadlyy

2

1 reference

Europe PubMed Central

13 August 2017

Yvonne Fierz

3

1 reference

Europe PubMed Central

13 August 2017

Nyosha Alikhani

4

1 reference

Europe PubMed Central

13 August 2017

Hui Sun

5

1 reference

Europe PubMed Central

13 August 2017

Shoshana Yakar

6

1 reference

Europe PubMed Central

13 August 2017

Derek Leroith

7

1 reference

Europe PubMed Central

13 August 2017

publication date

7 January 2012

1 reference

Europe PubMed Central

13 August 2017

Breast Cancer Research

1 reference

Europe PubMed Central

13 August 2017

14

1 reference

Europe PubMed Central

13 August 2017

1

1 reference

Europe PubMed Central

13 August 2017

R8

1 reference

Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.1186/bcr3089

0 references

MYC and Breast Cancer

1 reference

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30 September 2017

Diabetes mellitus and breast cancer outcomes: a systematic review and meta-analysis.

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Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation

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30 September 2017

Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496123

30 September 2017

Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496123

30 September 2017

Global estimates of the prevalence of diabetes for 2010 and 2030

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30 September 2017

Sp-1 and c-Myc mediate lysophosphatidic acid-induced expression of vascular endothelial growth factor in ovarian cancer cells via a hypoxia-inducible factor-1-independent mechanism

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Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women

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Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis

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Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

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30 September 2017

MYC in breast tumor progression

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30 September 2017

Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis

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30 September 2017

Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis

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30 September 2017

Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence

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30 September 2017

c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model.

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30 September 2017

Diabetes mellitus and risk of breast cancer: a meta-analysis

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30 September 2017

Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer

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30 September 2017

Matrix metalloproteinases and tumor metastasis

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Genes that mediate breast cancer metastasis to lung

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Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

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Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses

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Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line

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30 September 2017

Nutrition and lifestyle factors on the risk of developing breast cancer

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30 September 2017

The GH-IGF-I axis and breast cancer.

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30 September 2017

c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

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30 September 2017

Tyrosine kinase signalling in breast cancer: insulin-like growth factors and their receptors in breast cancer.

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30 September 2017

Matrix metalloproteinases in tumor invasion

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30 September 2017

Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis

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Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice

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30 September 2017

Determination of c-myc amplification and overexpression in breast cancer patients: evaluation of its prognostic value against c-erbB-2, cathepsin-D and clinicopathological characteristics using univariate and multivariate analysis

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Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

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30 September 2017

Insulin-stimulated cell growth in insulin receptor substrate-1-deficient ZR-75-1 cells is mediated by a phosphatidylinositol-3-kinase-independent pathway

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30 September 2017

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30 September 2017

Elevated insulin receptor content in human breast cancer

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30 September 2017

Structure, Evolution, Expression and Regulation of Insulin-Like Growth Factors I and II

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30 September 2017

Hormone responsive human breast cancer in long-term tissue culture: effect of insulin

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Insulin-like growth factors modulate the growth inhibitory effects of retinoic acid on MCF-7 breast cancer cells

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Possible modes of action of growth factors and tumor promoters in the activation of the c-myc gene in Swiss 3T3 fibroblasts

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Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent

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Explant-cell culture of primary mammary tumors from MMTV-c-Myc transgenic mice

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Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc.

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The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults

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https://pubmed.ncbi.nlm.nih.gov/22226054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased prevalence of prior breast cancer in women with newly diagnosed diabetes

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https://pubmed.ncbi.nlm.nih.gov/22226054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of c-myc gene and overexpression of c-Myc protein in breast cancer and adjacent non-neoplastic tissue

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https://pubmed.ncbi.nlm.nih.gov/22226054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of adipocyte beta3-adrenergic receptor activation on the type 2 diabetic MKR mice

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https://pubmed.ncbi.nlm.nih.gov/22226054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1

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https://pubmed.ncbi.nlm.nih.gov/22226054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/BCR3089

1 reference

Europe PubMed Central

13 August 2017

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1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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