Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory (Q36399652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+)

5 January 2020

main subject

apoptotic process

0 references

1 reference

1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine

60319

1 reference

60320

phosphocholine cation

1 reference

18132

low-density lipoprotein

1 reference

1 reference

1-O-palmitoyl-sn-glycero-3-phosphocholine

566274

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Gregg J Silverman

5

1 reference

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5 January 2020

author name string

Mi-Kyung Chang

1

1 reference

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5 January 2020

Yury I Miller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Ganesamoorthy Subbanagounder

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Judith A Berliner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Joseph L Witztum

7

1 reference

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5 January 2020

language of work or name

English

0 references

publication date

1 December 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

5 January 2020

published in

1 reference

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5 January 2020

volume

200

1 reference

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5 January 2020

issue

11

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5 January 2020

page(s)

1359-1370

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Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease

5 January 2020

cites work

1 reference

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Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury

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Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

30 September 2017

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Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserine

30 September 2017

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A blast from the past: clearance of apoptotic cells regulates immune responses.

30 September 2017

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I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation

30 September 2017

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Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36

30 September 2017

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30 September 2017

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Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta

30 September 2017

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The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium

30 September 2017

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Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

30 September 2017

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Apoptosis in atherosclerosis: focus on oxidized lipids and inflammation

30 September 2017

1 reference

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

30 September 2017

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Atherosclerosis. the road ahead

30 September 2017

1 reference

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Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein

30 September 2017

1 reference

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Immunological responses to oxidized LDL.

30 September 2017

1 reference

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Bioactive phospholipid oxidation products

30 September 2017

1 reference

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Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

30 September 2017

1 reference

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Antibodies to oxidised LDL.

30 September 2017

1 reference

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The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein

30 September 2017

1 reference

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30 September 2017

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Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition

30 September 2017

1 reference

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Apoptotic cells as immunogen and antigen in the antiphospholipid syndrome

30 September 2017

1 reference

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Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease

30 September 2017

1 reference

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Atherosclerosis — An Inflammatory Disease

30 September 2017

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Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

30 September 2017

1 reference

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Mitochondria and apoptosis

30 September 2017

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Systemic exposure to irradiated apoptotic cells induces autoantibody production

30 September 2017

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A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice

30 September 2017

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The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins)

30 September 2017

1 reference

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Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner

30 September 2017

1 reference

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Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein

30 September 2017

1 reference

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Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma

30 September 2017

1 reference

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

30 September 2017

1 reference

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Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae

30 September 2017

1 reference

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Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211955

Human anti-phosphorylcholine antibodies share idiotopes and are self-binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211955

Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7.

30 September 2017

1 reference

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All ApoB-containing lipoproteins induce monocyte chemotaxis and adhesion when minimally modified. Modulation of lipoprotein bioactivity by platelet-activating factor acetylhydrolase

28 June 2018

1 reference

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Sequence changes at the V-D junction of the VH1 heavy chain of anti-phosphocholine antibodies alter binding to and protection against Streptococcus pneumoniae

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211955

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211955

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

28 June 2018

1 reference

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The frequency of phosphorylcholine-specific B cells in conventional and germfree BALB/C mice

28 June 2018

1 reference

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Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus

28 June 2018

1 reference

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

21 September 2018

1 reference

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Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion

21 September 2018

1 reference

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Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway

21 September 2018

1 reference

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The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells

21 September 2018

1 reference

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Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.

21 September 2018

1 reference

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Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production.

21 September 2018

1 reference

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Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions

21 September 2018

1 reference

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Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation

21 September 2018

1 reference

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Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects?

21 September 2018

1 reference

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Risk factors for cardiovascular disease in systemic lupus erythematosus

21 September 2018

1 reference

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Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 September 2018

1 reference

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5 December 2018

Gone but not forgotten

1 reference

12 December 2020

C-C and C-X-C chemokines trigger firm adhesion of monocytes to vascular endothelium under flow conditions

1 reference

12 December 2020

The Clonal Selection Theory: what it really is and why modern challenges are misplaced

1 reference

12 December 2020

Subpopulations of antibodies to phosphocholine in human serum

1 reference

12 December 2020

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

1 reference

12 December 2020

Enhancement of macrophage phagocytosis upon iC3b deposition on apoptotic cells

1 reference

12 December 2020

Lysophosphatidylcholine: a chemoattractant to human T lymphocytes

1 reference

12 December 2020

Monoclonal anticardiolipin autoantibodies established from the (New Zealand white x BXSB)F1 mouse model of antiphospholipid syndrome cross-react with oxidized low-density lipoprotein

1 reference

12 December 2020

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

1 reference

12 December 2020

Blebs and apoptotic bodies are B cell autoantigens

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12 December 2020

Identifiers

DOI

10.1084/JEM.20031763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15583011%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

15583011

1 reference