The action of Bax and bcl-2 on T cell selection (Q36401807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9743531%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

The action of Bax and bcl-2 on T cell selection (English)

1 reference

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4 December 2019

5

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4 December 2019

author name string

O Williams

1

1 reference

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4 December 2019

T Norton

2

1 reference

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4 December 2019

M Halligey

3

1 reference

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4 December 2019

D Kioussis

4

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4 December 2019

language of work or name

English

0 references

publication date

1 September 1998

1 reference

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Journal of Experimental Medicine

4 December 2019

published in

1 reference

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4 December 2019

volume

188

1 reference

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4 December 2019

issue

6

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4 December 2019

page(s)

1125-1133

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Bcl-2 and Bax function independently to regulate cell death

4 December 2019

cites work

1 reference

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T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection.

30 September 2017

1 reference

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In vitro positive selection of alpha beta TCR transgenic thymocytes by a conditionally immortalized cortical epithelial clone.

30 September 2017

1 reference

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Apoptosis by death factor

30 September 2017

1 reference

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Bax alpha perturbs T cell development and affects cell cycle entry of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Lineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis

30 September 2017

1 reference

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The role of intracellular signalling pathways regulating thymocyte and leukemic T cell apoptosis

30 September 2017

1 reference

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T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

30 September 2017

1 reference

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Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

30 September 2017

1 reference

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

30 September 2017

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Fetal thymic organ cultures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

T-cell receptor-specific monoclonal antibodies against a V beta 11-positive mouse T-cell clone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Activation events during thymic selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

The proto-oncogene Bcl-2 and its role in regulating apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

Overexpressed Bcl-x(L) prevents bacterial superantigen-induced apoptosis of thymocytes in vitro.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

BCL-XL-regulated apoptosis in T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

CD69 expression during selection and maturation of CD4+8+ thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Susceptibility and resistance to antigen-induced apoptosis in the thymus of transgenic mice.

21 January 2018

1 reference

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Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212546

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

21 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Fas modulation of apoptosis during negative selection of thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

Bcl-2 counters apoptosis by Bax heterodimerization-dependent and -independent mechanisms in the T-cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.6.1125

bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9743531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.188.6.1125

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9743531%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9743531%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9743531%20AND%20SRC:MED&resulttype=core&format=json