Diabetic neuropathy and oxidative stress (Q36408693)

14 August 2017

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title

Diabetic neuropathy and oxidative stress (English)

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14 August 2017

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Rodica Pop-Busui

1

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author name string

Anders Sima

series ordinal

2

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PubMed ID

16506271

14 August 2017

Martin Stevens

series ordinal

3

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14 August 2017

1 July 2006

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Diabetes - Metabolism: Research and Reviews

14 August 2017

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14 August 2017

22

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14 August 2017

4

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14 August 2017

257-273

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The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy

14 August 2017

1 reference

Free radicals in medicine. II. Involvement in human disease

21 January 2018

1 reference

In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography

21 January 2018

1 reference

Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension.

21 January 2018

1 reference

In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation.

21 January 2018

1 reference

Mechanisms underlying endothelial dysfunction in diabetes mellitus

21 January 2018

1 reference

Oxidative stress: oxidants and antioxidants

21 January 2018

1 reference

Disruption of vascular signalling by the reaction of nitric oxide with superoxide: implications for cardiovascular disease

21 January 2018

1 reference

Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury.

21 January 2018

1 reference

Proinsulin C-peptide replacement in type 1 diabetic BB/Wor-rats prevents deficits in nerve fiber regeneration

21 January 2018

1 reference

Insulin-like growth factor replacement therapy for diabetic neuropathy: experimental basis

21 January 2018

1 reference

Autonomic nervous system and diabetes. Histological and histochemical study of the autonomic nerve fibers of the urinary bladder in diabetic patients

21 January 2018

1 reference

Metabolic benefits deriving from chronic vitamin C supplementation in aged non-insulin dependent diabetics.

21 January 2018

1 reference

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

21 January 2018

1 reference

7 January 2021

Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial

1 reference

7 January 2021

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

7 January 2021

Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus

1 reference

7 January 2021

Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats

1 reference

7 January 2021

Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats.

1 reference

7 January 2021

Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids

1 reference

7 January 2021

Metabolic and vascular factors in the pathogenesis of diabetic neuropathy

1 reference

7 January 2021

Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor

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7 January 2021

Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease

1 reference

7 January 2021

Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration

1 reference

7 January 2021

Peripheral nerve dysfunction in experimental diabetes is mediated by cyclooxygenase-2 and oxidative stress

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7 January 2021

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

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7 January 2021

A radical explanation for glucose-induced beta cell dysfunction

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7 January 2021

Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy

1 reference

7 January 2021

Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress.

1 reference

7 January 2021

Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve.

1 reference

7 January 2021

Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation.

1 reference

7 January 2021

Antioxidant characterization. Methodology and mechanism

1 reference

7 January 2021

Antioxidants in human health and disease

1 reference

7 January 2021

Antioxidant nutrients and immune functions--introduction

1 reference

7 January 2021

The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

1 reference

7 January 2021

Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine

1 reference

7 January 2021

Hypochlorous Acid-Induced Base Modifications in Isolated Calf Thymus DNA

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7 January 2021

8-Hydroxydeoxyguanosine as a urinary biomarker of oxidative DNA damage.

1 reference

7 January 2021

Apparent inactivation of alpha 1-antiproteinase by sulphur-containing radicals derived from penicillamine

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7 January 2021

Lack of influence of dietary nitrate/nitrite on plasma nitrotyrosine levels measured using a competitive inhibition of binding ELISA assay

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7 January 2021

Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha

1 reference

7 January 2021

Analysis of F2-isoprostanes as indicators of non-enzymatic lipid peroxidation in vivo by gas chromatography-mass spectrometry: development of a solid-phase extraction procedure

1 reference

7 January 2021

Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage

1 reference

7 January 2021

Formation of F2-isoprostanes during aortic endothelial cell-mediated oxidation of low density lipoprotein

1 reference

7 January 2021

New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.

1 reference

7 January 2021

Determination of carbonyl content in oxidatively modified proteins

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7 January 2021

Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production

1 reference

7 January 2021

Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase?

1 reference

7 January 2021

High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.

1 reference

7 January 2021

Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells

1 reference

7 January 2021

Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis.

1 reference

7 January 2021

Role of oxygen derived radicals for vascular dysfunction in the diabetic heart: prevention by alpha-tocopherol?

1 reference

7 January 2021

Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta

1 reference

7 January 2021

Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications

1 reference

7 January 2021

Protein glycation and oxidative stress in diabetes mellitus and ageing

1 reference

7 January 2021

Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes

1 reference

7 January 2021

Superoxide production from nonenzymatically glycated protein

1 reference

7 January 2021

Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions.

1 reference

7 January 2021

Oxidative damage to DNA in diabetes mellitus

1 reference

7 January 2021

Enhanced serum levels of thiobarbituric-acid-reactive substances in diabetes mellitus

1 reference

7 January 2021

Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications

1 reference

7 January 2021

Relation of Lipid Peroxides to Macrovascular Disease in Type 2 Diabetes

1 reference

7 January 2021

A comparison of different methods of assessing free radical activity in type 2 diabetes and peripheral vascular disease

1 reference

7 January 2021

Lipid peroxide levels of serum lipoprotein fractions of diabetic patients

1 reference

7 January 2021

Increased diene conjugates in diabetic subjects with microangiopathy

1 reference

7 January 2021

Plasma oxidizability in subjects with normal glucose tolerance, impaired glucose tolerance, and NIDDM.

1 reference

7 January 2021

Plasma 8-epi-PGF2 alpha levels are elevated in individuals with non-insulin dependent diabetes mellitus

1 reference

7 January 2021

Elevated levels of authentic plasma hydroperoxides in NIDDM.

1 reference

7 January 2021

Relationships between plasma measures of oxidative stress and metabolic control in NIDDM

1 reference

7 January 2021

Free radicals in diabetic endothelial cell dysfunction

1 reference

7 January 2021

Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor.

1 reference

7 January 2021

Oxidized Low Density Lipoproteins: a Role in the Pathogenesis of Atherosclerosis in Diabetes?

1 reference

7 January 2021

Sympathetic dysfunction in type 1 diabetes: association with impaired myocardial blood flow reserve and diastolic dysfunction

1 reference

7 January 2021

Role of oxidative stress in development of complications in diabetes

1 reference

7 January 2021

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

7 January 2021

Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

1 reference

7 January 2021

Metabolic abnormalities in diabetic peripheral nerve: Relation to impaired function

1 reference

7 January 2021

Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy

1 reference

7 January 2021

New Insights Into Diabetic Polyneuropathy

1 reference

7 January 2021

Oxidative stress in the pathogenesis of diabetic neuropathy

1 reference

7 January 2021

Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

1 reference

7 January 2021

Oxidative stress is associated with adiposity and insulin resistance in men.

1 reference

7 January 2021

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes

1 reference

7 January 2021

Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance

1 reference

7 January 2021

Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

1 reference

7 January 2021

Reduced antioxidant status in obese children with multimetabolic syndrome

1 reference

7 January 2021

Oxidative protein damage in type I diabetic patients with and without complications

1 reference

7 January 2021

Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome

1 reference

7 January 2021

Free radicals and disease

1 reference

7 January 2021

Oxidative protein damage in early stage Type 1 diabetic patients

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7 January 2021

Alpha-lipoic acid: the metabolic antioxidant

1 reference

7 January 2021

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

1 reference

7 January 2021

Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis.

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7 January 2021

Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane

1 reference

7 January 2021

Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid

1 reference

7 January 2021

Effects of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils

1 reference

7 January 2021

Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity

1 reference

7 January 2021

Abnormal glutathione metabolism and increased cytotoxicity caused by H2O2 in human umbilical vein endothelial cells cultured in high glucose medium

1 reference

7 January 2021

Ascorbate: the most effective antioxidant in human blood plasma

1 reference

7 January 2021

Comparison of antioxidant activities of tocopherols alone and in pharmaceutical formulations

1 reference

7 January 2021

Taurine: biological update

1 reference

7 January 2021

Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat

1 reference

7 January 2021

Nonosmotic diabetic cataracts.

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7 January 2021

Antioxidants reverse the antiproliferative effect of high glucose and advanced glycosylation end products in cultured rat mesangial cells

1 reference

7 January 2021

Effects of taurine on protein phosphorylation in mammalian tissues

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7 January 2021

Depletion of taurine in experimental diabetic neuropathy: implications for nerve metabolic, vascular, and functional deficits

1 reference

7 January 2021

Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy

1 reference

7 January 2021

Strategies of antioxidant defense

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7 January 2021

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

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7 January 2021

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

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7 January 2021

Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy

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7 January 2021

Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid

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7 January 2021

Susceptibility to diabetic neuropathy in patients with insulin dependent diabetes mellitus is associated with a polymorphism at the 5' end of the aldose reductase gene

1 reference

7 January 2021

Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl

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7 January 2021

Sorbitol, osmoregulation, and the complications of diabetes

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7 January 2021

Osmoregulation by slow changes in aldose reductase and rapid changes in sorbitol flux

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7 January 2021

Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil

1 reference

7 January 2021

Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group

1 reference

7 January 2021

Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage

1 reference

7 January 2021

Complications: neuropathy, pathogenetic considerations

1 reference

7 January 2021

Preventive effect of long-term aldose reductase inhibition (ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic Bio-Breeding rat

1 reference

7 January 2021

Glutathione redox state is not the link between polyol pathway activity and myo-inositol-related Na+-K+-ATPase defect in experimental diabetic neuropathy

1 reference

7 January 2021

Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease

1 reference

7 January 2021

Hyperglycemic pseudohypoxia and diabetic complications.

1 reference

7 January 2021

The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat.

1 reference

7 January 2021

Pathology and pathogenetic mechanisms of diabetic neuropathy.

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7 January 2021

Neural dysfunction and metabolic imbalances in diabetic rats. Prevention by acetyl-L-carnitine

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7 January 2021

Functional aspects and pathogenetic considerations of the neuropathy in the spontaneously diabetic BB-Wistar rat

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7 January 2021

Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo

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7 January 2021

Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy.

1 reference

7 January 2021

High-performance liquid chromatography-electrochemical detection of antioxidants in vertebrate lens: glutathione, tocopherol, and ascorbate

1 reference

7 January 2021

Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-alpha-lipoic acid

1 reference

7 January 2021

Interaction between osmotic and oxidative stress in diabetic precataractous lens: studies with a sorbitol dehydrogenase inhibitor

1 reference

7 January 2021

Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats

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7 January 2021

Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats

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7 January 2021

Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice.

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7 January 2021

Contributions of polyol pathway to oxidative stress in diabetic cataract.

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7 January 2021

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens

1 reference

7 January 2021

Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

1 reference

7 January 2021

Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study

1 reference

7 January 2021

Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy

1 reference

7 January 2021

Protein kinase C and the development of diabetic vascular complications

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7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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7 January 2021

The potential for isoenzyme-selective modulation of protein kinase C.

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7 January 2021

Signal transduction by protein kinase C in mammalian cells

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7 January 2021

The sevenfold way of PKC regulation

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7 January 2021

Protein kinase C signaling and oxidative stress

1 reference

7 January 2021

High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species

1 reference

7 January 2021

Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice

1 reference

7 January 2021

3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

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7 January 2021

Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction

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7 January 2021

Nonenzymatic glycosylation of peripheral nerve protein in diabetes mellitus

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7 January 2021

Excessive nonenzymatic glycosylation of peripheral and central nervous system myelin components in diabetic rats.

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7 January 2021

Metabolism of fructose-3-phosphate in the diabetic rat lens

1 reference

7 January 2021

The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

1 reference

7 January 2021

Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells

1 reference

7 January 2021

Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: a possible role for NGF in the pathogenesis of diabetic neuropathy

1 reference

7 January 2021

Effect of Aminoguanidine on Functional and Structural Abnormalities in Peripheral Nerve of STZ-Induced Diabetic Rats

1 reference

7 January 2021

Function and regulation of prostaglandin synthase-2.

1 reference

7 January 2021

Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide

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7 January 2021

Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy

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7 January 2021

Oxidative damage of cardiomyocytes is limited by extracellular regulated kinases 1/2-mediated induction of cyclooxygenase-2

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7 January 2021

Role of prostaglandin H2 as an endothelium-derived contracting factor in diabetic state

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7 January 2021

Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats

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7 January 2021

Decreased vascular prostacyclin in experimental diabetes

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7 January 2021

Diverse prostaglandin receptors activate distinct signal transduction pathways in rat myometrium

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7 January 2021

Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta

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7 January 2021

Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: influence of tocopherol as antioxidant

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7 January 2021

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

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7 January 2021

Antioxidants, diabetes and endothelial dysfunction

1 reference

7 January 2021

Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway

1 reference

7 January 2021

Mitochondrial nitric oxide synthase, oxidative stress and apoptosis

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7 January 2021

Nitric oxide and its role in lipid peroxidation.

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7 January 2021

Role of nitric oxide in inflammation-mediated neurodegeneration.

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7 January 2021

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

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7 January 2021

Ultrastructural changes and immunohistochemical localization of nitric oxide synthase, advanced glycation end products and NF-kappa B in aorta of streptozotocin treated Mongolian gerbils

1 reference

7 January 2021

What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?

1 reference

7 January 2021

Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation.

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7 January 2021

Poly (ADP-ribose) polymerase, nitric oxide and cell death

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7 January 2021

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

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7 January 2021

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

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7 January 2021

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

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7 January 2021

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite

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7 January 2021

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

1 reference

7 January 2021

Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase

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7 January 2021

Oxidative stress inhibits the mitochondrial import of preproteins and leads to their degradation

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7 January 2021

Mitochondrial permeability transition and oxidative stress

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7 January 2021

Inhibition of apoptosis by antioxidants in the human HL-60 leukemia cell line

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7 January 2021

Inhibition of bile-salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E

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7 January 2021

Increase in TUNEL positive cells in aorta from diabetic rats.

1 reference

7 January 2021

Expression and localization of p53 and bcl-2 in healing wounds in diabetic and nondiabetic mice

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7 January 2021

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin

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7 January 2021

Oxidative stress and programmed cell death in diabetic neuropathy

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7 January 2021

Neurons undergo apoptosis in animal and cell culture models of diabetes.

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7 January 2021

Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction

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7 January 2021

Sensory neurons with activated caspase-3 survive long-term experimental diabetes

1 reference

7 January 2021

Does diabetes target ganglion neurones? Progressive sensory neurone involvement in long-term experimental diabetes.

1 reference

7 January 2021

C-peptide prevents nociceptive sensory neuropathy in type 1 diabetes

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7 January 2021

The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats.

1 reference

7 January 2021

Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy.

1 reference

7 January 2021

Non-enzymatic glycation of peripheral nerve proteins in human diabetics

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7 January 2021

Neurotrophic factors and diabetic peripheral neuropathy

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7 January 2021

New insights into the metabolic and molecular basis for diabetic neuropathy

1 reference

7 January 2021

Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar rats

1 reference

7 January 2021

Timolol Treatment After Myocardial Infarction in Diabetic Patients

1 reference

7 January 2021

Insulin, C-peptide, hyperglycemia, and central nervous system complications in diabetes

1 reference

7 January 2021

Type 1 diabetic neuropathy and C-peptide

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7 January 2021

Molecular alterations underlie nodal and paranodal degeneration in type 1 diabetic neuropathy and are prevented by C-peptide

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7 January 2021

C-peptide enhances insulin-mediated cell growth and protection against high glucose-induced apoptosis in SH-SY5Y cells

1 reference

7 January 2021

An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense

1 reference

7 January 2021

A multicentre trial of the aldose-reductase inhibitor, tolrestat, in patients with symptomatic diabetic neuropathy

1 reference

7 January 2021

Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.

1 reference

7 January 2021

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study

1 reference

7 January 2021

Fidarestat (SNK-860), a potent aldose reductase inhibitor, normalizes the elevated sorbitol accumulation in erythrocytes of diabetic patients

1 reference

7 January 2021

Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic sensorimotor polyneuropathy

1 reference

7 January 2021

The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study

1 reference

7 January 2021

alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria

1 reference

7 January 2021

Effects of alpha-lipoic acid on microcirculation in patients with peripheral diabetic neuropathy

1 reference

7 January 2021

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy

1 reference

7 January 2021

Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from clinical trials

1 reference

7 January 2021

Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie

1 reference

7 January 2021

The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.

1 reference

7 January 2021

The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy

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7 January 2021

Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group

1 reference

7 January 2021

Slowing of peripheral motor nerve conduction was ameliorated by aminoguanidine in streptozocin-induced diabetic rats

1 reference

7 January 2021

Effect of aminoguanidine on the frequency of neuroaxonal dystrophy in the superior mesenteric sympathetic autonomic ganglia of rats with streptozocin-induced diabetes

1 reference

7 January 2021

Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats

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7 January 2021

Comparison of the effect of α-lipoic acid and α-tocopherol supplementation on measures of oxidative stress

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7 January 2021

Oxidative stress and diabetic neuropathy: pathophysiological mechanisms and treatment perspectives

1 reference

7 January 2021

Antioxidant vitamins and their influence in diabetes mellitus

1 reference

7 January 2021

Vitamin E: the evidence for multiple roles in cancer

1 reference

7 January 2021

Supplementation of Diets with α-Tocopherol Reduces Serum Concentrations of γ- and δ-Tocopherol in Humans

1 reference

7 January 2021

The comparison of vitamin C and vitamin E on the protein oxidation of diabetic rats

1 reference

7 January 2021

Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat

1 reference

7 January 2021

Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.

1 reference

7 January 2021

Acetyl-L-carnitine for symptomatic diabetic neuropathy

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7 January 2021

Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials

1 reference

7 January 2021

Vitamin E in diabetes. Increased oxidative stress and its prevention as a strategy to prevent vascular complications?

1 reference

7 January 2021

A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.625

1 reference

14 August 2017

1 reference

PubMed ID

16506271