Refractory epilepsy: mechanisms and solutions (Q36419584)

14 August 2017

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title

Refractory epilepsy: mechanisms and solutions (English)

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14 August 2017

2

Martin J Brodie

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author name string

Patrick Kwan

series ordinal

1

1 reference

PubMed ID

16533143

14 August 2017

Martin J Brodie

series ordinal

2

1 reference

14 August 2017

1 March 2006

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

14 August 2017

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14 August 2017

6

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14 August 2017

3

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14 August 2017

397-406

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Epidemiology of the epilepsies

14 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Descriptive epidemiology of epilepsy: contributions of population-based studies from Rochester, Minnesota

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Early identification of refractory epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The natural history of epilepsy: an epidemiological view.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League Against Epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

On the cellular and network bases of epileptic seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The neurobiology of antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Channelopathies as a genetic cause of epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The mechanisms of action of commonly used antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Current evidence indicates that antiepileptic drugs are anti-ictal, not antiepileptic

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Is the underlying cause of epilepsy a major prognostic factor for recurrence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Does the cause of localisation-related epilepsy influence the response to antiepileptic drug treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

A randomized, controlled trial of surgery for temporal-lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Risk to verbal memory following anterior temporal lobectomy in patients with severe left-sided hippocampal sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Vagus nerve stimulation therapy summary: five years after FDA approval

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Therapeutic mechanisms of vagus nerve stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

More fat and fewer seizures: dietary therapies for epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Efficacy and safety of the ketogenic diet for intractable childhood epilepsy: Korean multicentric experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

How long does it take for partial epilepsy to become intractable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

A novel mechanism underlying drug resistance in chronic epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Mechanisms of antiepileptic drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Potential role of drug transporters in the pathogenesis of medically intractable epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

MDR1 gene expression in brain of patients with medically intractable epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The impact of efflux transporters in the brain on the development of drugs for CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

A potassium channel mutation in neonatal human epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Non-competitive AMPA antagonists of 2,3-benzodiazepine type

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The AMPA-antagonist talampanel is neuroprotective in rodent models of focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII)

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Potential new methods for antiepileptic drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on kindling acquisition and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Recent advances with liposomes as pharmaceutical carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Drug transport to brain with targeted liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Seizure suppression in kindled rats by intraventricular grafting of an adenosine releasing synthetic polymer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The intracerebral administration of phenytoin using controlled-release polymers reduces experimental seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Present and future of deep brain stimulation for refractory epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Electrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Double-blind, randomized controlled pilot study of bilateral cerebellar stimulation for treatment of intractable motor seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Long-term amygdalohippocampal stimulation for refractory temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Brain stimulation for epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

An automated drug delivery system for focal epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Implantation of a closed-loop stimulation in the management of medically refractory focal epilepsy: a technical note

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Prediction of epileptic seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Suppression of kindled seizures by paracrine adenosine release from stem cell-derived brain implants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Anticonvulsant and antiepileptogenic effects mediated by adeno-associated virus vector neuropeptide Y expression in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Clinical trials of antiepileptic medications in newly diagnosed patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.3.397

21 January 2018

Identifiers

DOI

10.1586/14737175.6.3.397

1 reference

release_3vbnp3tzqbffjonual5oztomxy

14 August 2017

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https://api.fatcat.wiki/v0/release/3vbnp3tzqbffjonual5oztomxy

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24 November 2022

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PubMed ID

16533143

1 reference

PubMed ID

16533143