A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo (Q36421134)

14 August 2017

A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo (English)

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14 August 2017

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Jeffery D Molkentin

5

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author name string

Jennifer Davis

1

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14 August 2017

Adam R Burr

2

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14 August 2017

Gregory F Davis

3

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14 August 2017

Lutz Birnbaumer

4

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14 August 2017

language of work or name

English

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publication date

27 September 2012

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14 August 2017

11

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inferred from page(s)

published in

Developmental Cell

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14 August 2017

23

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14 August 2017

4

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14 August 2017

705-715

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describes a project that uses

14 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3505601/fullTextXML

inferred from PubMed Central ID database lookup

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Identifying functional single nucleotide polymorphisms in the human CArGome

30 September 2017

1 reference

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TRPC channels as effectors of cardiac hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

30 September 2017

1 reference

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Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation

30 September 2017

1 reference

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TRPC channels are necessary mediators of pathologic cardiac hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation

30 September 2017

1 reference

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TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization

30 September 2017

1 reference

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Cellular and molecular mechanisms of fibrosis

30 September 2017

1 reference

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NFATc is required for TGFbeta-mediated transcriptional regulation of fibronectin

30 September 2017

1 reference

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Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts

30 September 2017

1 reference

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Formation and function of the myofibroblast during tissue repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2.

30 September 2017

1 reference

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TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

30 September 2017

1 reference

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Increased vascular smooth muscle contractility in TRPC6-/- mice

30 September 2017

1 reference

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Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer

30 September 2017

1 reference

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AKAP12alpha, an atypical serum response factor-dependent target gene

30 September 2017

1 reference

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A TRPC1/TRPC3-mediated increase in store-operated calcium entry is required for differentiation of H19-7 hippocampal neuronal cells

30 September 2017

1 reference

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TGF-beta1 and angiotensin networking in cardiac remodeling

30 September 2017

1 reference

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Skeletal myosin heavy chain function in cultured lung myofibroblasts

30 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Myofibroblasts and mechano-regulation of connective tissue remodelling

30 September 2017

1 reference

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The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor.

30 September 2017

1 reference

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Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

30 September 2017

1 reference

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NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor

28 June 2018

1 reference

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Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

A critical role of serum response factor in myofibroblast differentiation during experimental oesophageal ulcer healing in rats

28 June 2018

1 reference

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Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3505601

Functional role of vanilloid transient receptor potential 4-canonical transient receptor potential 1 complex in flow-induced Ca2+ influx

21 September 2018

1 reference

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NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury

21 September 2018

1 reference

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Triterpenes promote keratinocyte differentiation in vitro, ex vivo and in vivo: a role for the transient receptor potential canonical (subtype) 6.

21 September 2018

1 reference

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Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta

21 September 2018

1 reference

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p38 inhibitors prevent TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23022034

12 December 2020

inferred from PubMed ID database lookup

TGF-beta-activated kinase 1 and TAK1-binding protein 1 cooperate to mediate TGF-beta1-induced MKK3-p38 MAPK activation and stimulation of type I collagen

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23022034

12 December 2020

inferred from PubMed ID database lookup

Tacrolimus impairs wound healing: a possible role of decreased nitric oxide synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23022034

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.DEVCEL.2012.08.017

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14 August 2017

1 reference

14 August 2017

1 reference