Polymorphisms in the p53 pathway. (Q36426763)

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18 January 2020

review article

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title

Polymorphisms in the p53 pathway (English)

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18 January 2020

3

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18 January 2020

author name string

Pietsch EC

series ordinal

1

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18 January 2020

Humbey O

series ordinal

2

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18 January 2020

language of work or name

English

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publication date

1 March 2006

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18 January 2020

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18 January 2020

volume

25

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18 January 2020

issue

11

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18 January 2020

page(s)

1602-1611

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Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

18 January 2020

cites work

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A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells

21 January 2018

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7 January 2021

Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer

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7 January 2021

Cutaneous squamous cell carcinoma and p53 codon 72 polymorphism: a need for screening?

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7 January 2021

Is p53 polymorphism maintained by natural selection?

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The codon 31 polymorphism of the p53-inducible gene p21 shows distinct differences between major ethnic groups

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7 January 2021

Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer

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7 January 2021

A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients

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7 January 2021

p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes

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7 January 2021

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

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Radiation-induced cell cycle arrest compromised by p21 deficiency

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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7 January 2021

p21 gene codon 31 polymorphism is associated with bladder cancer

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7 January 2021

Pocket proteins and cell cycle control

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7 January 2021

Association of p53 arginine polymorphism with skin cancer

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7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Cyclins and cdks in development and cancer: a perspective

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7 January 2021

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Association between human cancer and two polymorphisms occurring together in the p21Waf1/Cip1 cyclin-dependent kinase inhibitor gene

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7 January 2021

A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA.

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7 January 2021

Proline homozygosity in codon 72 of p53 is a factor of susceptibility for thyroid cancer

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7 January 2021

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

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7 January 2021

WAF1 genotype and endometrial cancer susceptibility

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

Molecular basis for heterogeneity of the human p53 protein

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7 January 2021

Clinical implications of the p53 tumor-suppressor gene

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7 January 2021

Association of codon 72 polymorphism of p53 with lower prostate cancer risk

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7 January 2021

Polymorphisms in the p53 gene in thyroid tumours and blood samples of children from areas in Belarus

1 reference

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7 January 2021

p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.

1 reference

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7 January 2021

p53 Mutations, Polymorphisms, and Haplotypes in Pakistani Ethnic Groups and Breast Cancer Patients

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7 January 2021

p53 polymorphisms in Russia and Belarus: correlation of the 2-1-1 haplotype frequency with longitude

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7 January 2021

Polymorphisms of p21 cyclin-dependent kinase inhibitor and malignant skin tumors

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7 January 2021

Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours

1 reference

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7 January 2021

p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review

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7 January 2021

p53 Codon 72 polymorphism and urothelial cancer risk

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7 January 2021

Identification of a PstI polymorphism in the p21Cip1/Waf1 cyclin-dependent kinase inhibitor gene

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7 January 2021

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

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7 January 2021

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

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7 January 2021

The codon 47 polymorphism in p53 is functionally significant.

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7 January 2021

Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.

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7 January 2021

Proliferating cell nuclear antigen (PCNA): a dancer with many partners

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7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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7 January 2021

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

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7 January 2021

G1 cell-cycle control and cancer

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7 January 2021

Primary structure polymorphism at amino acid residue 72 of human p53.

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7 January 2021

Polymorphisms in P21CIP1/WAF1 are not correlated with TP53 status in sporadic ovarian tumours

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7 January 2021

Association of specific genotype and haplotype of p53 gene with cervical cancer in India

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7 January 2021

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer

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7 January 2021

TP53 mutation, allelism and survival in non-small cell lung cancer

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7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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7 January 2021

The R72P P53 mutation is associated with familial breast cancer in Jewish women

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7 January 2021

p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

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7 January 2021

The IARC TP53 database: new online mutation analysis and recommendations to users

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7 January 2021

P53 codon 72 polymorphism and human papillomavirus type in relation to cervical cancer in South African women

1 reference

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7 January 2021

p53 polymorphic variants at codon 72 exert different effects on cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Analysis of CDKN1A polymorphisms: markers of cancer susceptibility?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 and p21 genetic polymorphisms and susceptibility to endometrial cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Polymorphisms in codon 31 of p21 and cervical cancer susceptibility in Korean women

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53-based blood test for p53PIN3 and risk for sporadic ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

1 reference

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7 January 2021

Transcription, apoptosis and p53: catch-22.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck: a case-control study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Evidence of gene deletion of p21 (WAF1/CIP1), a cyclin-dependent protein kinase inhibitor, in thyroid carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Lack of evidence of association of p21WAF1/CIP1 polymorphism with lung cancer susceptibility and prognosis in Taiwan

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 polymorphisms and haplotypes in different ethnic groups

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Association between the p21 codon 31 A1 (arg) allele and lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 codon 72 polymorphism and its association with bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 Codon 72 polymorphism is linked to the development and not the progression of benign and malignant laryngeal tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

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7 January 2021

P53 (codon 72) and P21 (codon 31) polymorphisms alter in vivo mRNA expression of p21.

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7 January 2021

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

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7 January 2021

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

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7 January 2021

Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines

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7 January 2021

Two polymorphic variants of wild-type p53 differ biochemically and biologically

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7 January 2021

The p53 codon 72 polymorphism in Thai nasopharyngeal carcinoma

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7 January 2021

Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival

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7 January 2021

Correlation of p21 gene codon 31 polymorphism and TNF-alpha gene polymorphism with nasopharyngeal carcinoma.

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7 January 2021

Prognostic significance of the proline form of p53 codon 72 polymorphism in nasopharyngeal carcinoma

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7 January 2021

Evaluation of the combined effect of p53 codon 72 polymorphism and hotspot mutations in response to anticancer drugs

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7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

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7 January 2021

WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Polymorphisms of H-ras-1 and p53 in breast cancer and lung cancer: a meta-analysis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Influences of lifestyle habits and p53 codon 72 and p21 codon 31 polymorphisms on gastric cancer risk in Taiwan

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

Association between p21 codon 31 polymorphism and esophageal cancer risk in a Taiwanese population.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209367

7 January 2021

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity

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7 January 2021

p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions.

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

p53 Codon 72 polymorphism predicts the pathologic response to neoadjuvant chemotherapy in patients with breast cancer

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7 January 2021