Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism (Q36435170)

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scientific article published on 15 October 2012

Language	Label	Description	Also known as
English	Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism	scientific article published on 15 October 2012

Statements

scholarly article

1 reference

Europe PubMed Central

14 August 2017

Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism (English)

1 reference

Europe PubMed Central

14 August 2017

0 references

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author name string

Krysten M Farjo

1

1 reference

Europe PubMed Central

14 August 2017

Rafal A Farjo

2

1 reference

Europe PubMed Central

14 August 2017

Stacey Halsey

3

1 reference

Europe PubMed Central

14 August 2017

Gennadiy Moiseyev

4

1 reference

Europe PubMed Central

14 August 2017

Jian-Xing Ma

5

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Europe PubMed Central

14 August 2017

language of work or name

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publication date

15 October 2012

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Europe PubMed Central

14 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

14 August 2017

32

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Europe PubMed Central

14 August 2017

24

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Europe PubMed Central

14 August 2017

5103-5115

1 reference

Europe PubMed Central

14 August 2017

Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510526

30 September 2017

Adipose tissue dysregulation in patients with metabolic syndrome

1 reference

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30 September 2017

Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses

1 reference

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Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.

1 reference

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Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection.

1 reference

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30 September 2017

Role of NADPH oxidase in atherosclerosis

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30 September 2017

NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology

1 reference

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30 September 2017

Retinol to retinol-binding protein (RBP) is low in obese adults due to elevated apo-RBP.

1 reference

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30 September 2017

Role of NADPH oxidase in retinal vascular inflammation.

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Insulin-sensitizing effects of exercise on adiponectin and retinol-binding protein-4 concentrations in young and middle-aged women.

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Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy

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Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone

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Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation

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30 September 2017

A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A

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30 September 2017

Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects

1 reference

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30 September 2017

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

1 reference

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Redox signaling in angiogenesis: role of NADPH oxidase

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Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects

1 reference

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Overview of retinoid metabolism and function

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Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases

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RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle.

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Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.

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30 September 2017

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

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30 September 2017

Retinopathy in diabetes

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30 September 2017

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

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Diabetes and atherosclerosis: epidemiology, pathophysiology, and management

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A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

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Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

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Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes

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Evidence for an essential role of megalin in transepithelial transport of retinol

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Differential nitric oxide production by microvascular and macrovascular endothelial cells

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Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

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Activation of nuclear factor-kappa B correlates with MCP-1 expression by human mesangial cells

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Role of nuclear factor-kappa B in atherogenesis

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Toll-like receptor 4 activation in microvascular endothelial cells triggers a robust inflammatory response and cross talk with mononuclear cells via interleukin-6.

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Microvascular and macrovascular endothelial cells produce different constrictor substances

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Diabetes and cardiovascular disease. The Framingham study

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Circulating retinol-binding protein 4 and metabolic syndrome in the elderly.

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Retinol-binding protein 4 and insulin resistance in preeclampsia

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Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness

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Serum retinol-binding protein 4 levels in patients with diabetic retinopathy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510526

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Retinol-binding protein-4 in women with untreated essential hypertension.

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Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly

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RBP-to-retinol ratio, but not total RBP, is elevated in patients with type 2 diabetes.

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Serum retinol binding protein 4 is related to insulin resistance and nonoxidative glucose metabolism in lean and obese women with normal glucose tolerance.

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Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

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TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells

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https://pubmed.ncbi.nlm.nih.gov/23071093

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based on heuristic

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Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinol binding protein-4 levels and clinical features of type 2 diabetes patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

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based on heuristic

inferred from PubMed ID database lookup

Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

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based on heuristic

inferred from PubMed ID database lookup

Elevation of plasma retinol-binding protein 4 and reduction of plasma adiponectin in subjects with cerebral infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High plasma retinol binding protein 4 (RBP4) is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in nonobese, nondiabetic patients with chronic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23071093

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00820-12

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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