Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage (Q36438918)

14 August 2017

Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage (English)

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14 August 2017

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A M Ghaleb

1

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14 August 2017

J P Katz

2

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14 August 2017

K H Kaestner

3

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14 August 2017

J X Du

4

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14 August 2017

V W Yang

5

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14 August 2017

language of work or name

English

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publication date

2 October 2006

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14 August 2017

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14 August 2017

26

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14 August 2017

16

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14 August 2017

2365-2373

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210022

14 August 2017

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cites work

KLF4, p21 and context-dependent opposing forces in cancer

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The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

30 September 2017

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The transcriptional targets of p53 in apoptosis control

30 September 2017

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Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage

30 September 2017

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Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression

30 September 2017

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Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia

30 September 2017

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In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

30 September 2017

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Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

30 September 2017

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Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer

30 September 2017

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Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage

30 September 2017

1 reference

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P53 and radiation responses

30 September 2017

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p53 has a direct apoptogenic role at the mitochondria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage

30 September 2017

1 reference

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Dissecting p53 tumor suppressor functions in vivo

30 September 2017

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The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

30 September 2017

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Radiotherapy and cellular signalling

30 September 2017

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The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

30 September 2017

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Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

30 September 2017

Surfing the p53 network

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Cooperative effects of genes controlling the G(2)/M checkpoint

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Identification and characterization of a p53 homologue in Drosophila melanogaster

30 September 2017

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The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Two potent nuclear localization signals in the gut-enriched Krüppel-like factor define a subfamily of closely related Krüppel proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

p53 is required for radiation-induced apoptosis in mouse thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

WAF1, a potential mediator of p53 tumor suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

Thymocyte apoptosis induced by p53-dependent and independent pathways.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2230633

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210022

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210022

Cell-cycle arrest versus cell death in cancer therapy

21 January 2018

1 reference

12 December 2020

Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach

1 reference

12 December 2020

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

12 December 2020

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.ONC.1210022

1 reference

14 August 2017

1 reference

14 August 2017

1 reference