Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors (Q36440736)

14 August 2017

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title

Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors (English)

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14 August 2017

Birgitte Holst

2

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Thue W Schwartz

object named as

Thue W Schwartz

series ordinal

1

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language of work or name

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1 January 2006

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Journal of Receptors and Signal Transduction

14 August 2017

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14 August 2017

26

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14 August 2017

1-2

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14 August 2017

107-128

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G protein-coupled receptor allosterism and complexing

14 August 2017

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International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology

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The inhibitory effect of gallamine on muscarinic receptors

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Allosteric regulation of G-protein-linked receptors

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Allosteric functioning of dimeric class C G-protein-coupled receptors.

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Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide

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A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

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The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

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Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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Oligomerization of G-protein-coupled transmitter receptors.

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Heterodimerization is required for the formation of a functional GABA(B) receptor

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Role of heteromer formation in GABAB receptor function

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Roles of G-protein-coupled receptor dimerization

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Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein

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Cooperative conformational changes in a G-protein-coupled receptor dimer, the leukotriene B(4) receptor BLT1.

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Cardiac muscarinic receptors. Cooperativity as the basis for multiple states of affinity.

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Activation mechanism of the heterodimeric GABA(B) receptor

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Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.

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Different functional roles of T1R subunits in the heteromeric taste receptors

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Multiple allosteric sites on muscarinic receptors

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Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors

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Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors

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Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

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Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR

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Principles: a model for the allosteric interactions between ligand binding sites within a dimeric GPCR.

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The effects of MK-0677, an oral growth hormone secretagogue, in patients with hip fracture

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Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men

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Changes in appetite and body weight in response to long-term oral administration of the ghrelin agonist GHRP-2 in growth hormone deficient children

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Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males

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10.1080/10799890600567570

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16595341