A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia. (Q36442837)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036362%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia (English)

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9 March 2020

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5

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author name string

Shadia E Nada

1

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9 March 2020

Jatin Tulsulkar

2

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9 March 2020

Aparna Raghavan

3

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9 March 2020

Kenneth Hensley

4

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publication date

2 October 2012

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Neurochemistry International

9 March 2020

published in

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volume

61

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issue

8

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page(s)

1357-1363

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describes a project that uses

9 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3513634/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2.

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Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection.

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Collapsin response mediator protein-2: an emerging pathologic feature and therapeutic target for neurodisease indications

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Emerging biological importance of central nervous system lanthionines.

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Proteomic identification of binding partners for the brain metabolite lanthionine ketimine (LK) and documentation of LK effects on microglia and motoneuron cell cultures

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NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

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Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

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Proteomic analysis of neonatal mouse brain: evidence for hypoxia- and ischemia-induced dephosphorylation of collapsin response mediator proteins

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Sirtuins: critical regulators at the crossroads between cancer and aging

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SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

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Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury

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Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury

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The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

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Enhanced neurogenesis after transient global ischemia in the dentate gyrus of the rat.

30 September 2017

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Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522

30 September 2017

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CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity.

30 September 2017

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21 September 2018

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21 September 2018

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10.1016/J.NEUINT.2012.09.013

21 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036362%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

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9 March 2020

PubMed publication ID

23036362

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036362%20AND%20SRC:MED&resulttype=core&format=json