Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview (Q36443604)

14 August 2017

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title

Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview (English)

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Isabel Tavares de Almeida

14 August 2017

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object named as

Tavares de Almeida I

5

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author name string

Castro R

1

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14 August 2017

Rivera I

2

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14 August 2017

Blom HJ

3

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14 August 2017

Jakobs C

4

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14 August 2017

1 February 2006

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Journal of Inherited Metabolic Disease

14 August 2017

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14 August 2017

29

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14 August 2017

3-20

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14 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s10545-006-0106-5

14 August 2017

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Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease.

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12 December 2020

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

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Hyperhomocysteinemia in chronic renal disease

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12 December 2020

Methionine-loading test: evaluation of adverse effects and safety in an epidemiological study

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Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study

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12 December 2020

Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease

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12 December 2020

Cystathionine beta-synthase polymorphisms and hyperhomocysteinaemia: an association study

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12 December 2020

C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease

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12 December 2020

Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.

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12 December 2020

The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17

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12 December 2020

The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.

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12 December 2020

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

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12 December 2020

Increased homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease

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12 December 2020

A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations

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12 December 2020

Genetic polymorphisms in folate and homocysteine metabolism as risk factors for DNA damage.

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12 December 2020

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter

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12 December 2020

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

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12 December 2020

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

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12 December 2020

Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine

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12 December 2020

Effects of DNA methylation on DNA-binding proteins and gene expression.

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12 December 2020

Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation

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12 December 2020

The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase

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12 December 2020

Methionine synthase reductase MTRR 66A > G has no effect on total homocysteine, folate, and Vitamin B12 concentrations in renal transplant patients

1 reference

12 December 2020

Low diagnostic value of fasting and post-methionine load homocysteine tests. A study in Dutch subjects with homocysteine test indications

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12 December 2020

Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus

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12 December 2020

Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults

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12 December 2020

Hyperhomocysteinemia and venous thrombosis: a meta-analysis.

1 reference

12 December 2020

Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood

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12 December 2020

Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia

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12 December 2020

Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase

1 reference

12 December 2020

Homocysteine and endothelial dysfunction: a link with cardiovascular disease

1 reference

12 December 2020

Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase

1 reference

12 December 2020

The pathogenesis of coronary artery disease. A possible role for methionine metabolism

1 reference

12 December 2020

Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.

1 reference

12 December 2020

Vitamins, homocysteine and cardiovascular risk

1 reference

12 December 2020

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

1 reference

12 December 2020

Methionine metabolism in mammals. Adaptation to methionine excess

1 reference

12 December 2020

A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

1 reference

12 December 2020

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

1 reference

12 December 2020

The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjects

1 reference

12 December 2020

Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.

1 reference

12 December 2020

The effect of reduced glomerular filtration rate on plasma total homocysteine concentration

1 reference

12 December 2020

Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene

1 reference

12 December 2020

Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans

1 reference

12 December 2020

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

12 December 2020

The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans

1 reference

12 December 2020

CpNpG methylation in mammalian cells

1 reference

12 December 2020

The effect of 677C-->T and 1298A-->C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects

1 reference

12 December 2020

Folic acid responsive postmenopausal homocysteinemia.

1 reference

12 December 2020

High prevalence of a mutation in the cystathionine beta-synthase gene.

1 reference

12 December 2020

Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant

1 reference

12 December 2020

The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes.

1 reference

12 December 2020

Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease

1 reference

12 December 2020

Homocysteine and transmethylations in uremia.

1 reference

12 December 2020

Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration

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12 December 2020

Hyperhomocysteinemia, vascular function and atherosclerosis: effects of vitamins

1 reference

12 December 2020

Polymorphisms in the CBS gene associated with decreased risk of coronary artery disease and increased responsiveness to total homocysteine lowering by folic acid

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12 December 2020

D-amino acids in aging erythrocytes

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12 December 2020

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12 December 2020

Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in

1 reference

12 December 2020

Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease.

1 reference

12 December 2020

A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk

1 reference

12 December 2020

Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L

1 reference

12 December 2020

Homocysteine and hypomethylation. A novel link to vascular disease

1 reference

12 December 2020

Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice

1 reference

12 December 2020

Blood levels of homocysteine and increased risks of cardiovascular disease: causal or casual?

1 reference

12 December 2020

Gene-nutrient and gene-gene interactions of controlled folate intake by Japanese women

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12 December 2020

Hyperhomocysteinemia in terms of steady-state kinetics

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12 December 2020

Homocysteine and cysteine: determinants of plasma levels in middle-aged and elderly subjects

1 reference

12 December 2020

Common mutation in the methylenetetrahydrofolate reductase gene offers no support for mild hyperhomocysteinemia being a causal risk factor for cardiovascular disease

1 reference

12 December 2020

Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular disease

1 reference

12 December 2020

Genetic determinants of hyperhomocysteinaemia: the roles of cystathionine beta-synthase and 5,10-methylenetetrahydrofolate reductase

1 reference

12 December 2020

Effect of heterozygosity for the methionine synthase 2756 A-->G mutation on the risk for recurrent cardiovascular events

1 reference

12 December 2020

A 31 bp VNTR in the cystathionine beta-synthase (CBS) gene is associated with reduced CBS activity and elevated post-load homocysteine levels

1 reference

12 December 2020

Folic acid metabolism and mechanisms of neural tube defects.

1 reference

12 December 2020

High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa

1 reference

12 December 2020

The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort

1 reference

12 December 2020

Fasting vs Nonfasting Plasma Homocysteine Concentrations for Diagnosis of Hyperhomocysteinemia

1 reference

12 December 2020

Biological and clinical implications of the MTHFR C677T polymorphism

1 reference

12 December 2020

Hyperhomocysteinemia is related to residual glomerular filtration and folate, but not to methylenetetrahydrofolate-reductase and methionine synthase polymorphisms, in supplemented end-stage renal disease patients undergoing hemodialysis

1 reference

12 December 2020

Genetics of hyperhomocysteinaemia in cardiovascular disease

1 reference

12 December 2020

The cblD defect causes either isolated or combined deficiency of methylcobalamin and adenosylcobalamin synthesis.

1 reference

12 December 2020

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

1 reference

12 December 2020

Effect of glutamate carboxypeptidase II and reduced folate carrier polymorphisms on folate and total homocysteine concentrations in dialysis patients.

1 reference

12 December 2020

Consequences of homocysteine export and oxidation in the vascular system

1 reference

12 December 2020

Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment

1 reference

12 December 2020

5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylation

1 reference

12 December 2020

Homocysteine metabolism in endothelial cells of a patient homozygous for cystathionine beta-synthase (CS) deficiency

1 reference

12 December 2020

1 reference

12 December 2020

Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction

1 reference

12 December 2020

A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations

1 reference

12 December 2020

Acute hyperhomocysteinaemia and endothelial dysfunction

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12 December 2020

Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease

1 reference

12 December 2020

Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study

1 reference

12 December 2020

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

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12 December 2020

Cellular aspects of folate and antifolate membrane transport.

1 reference

12 December 2020

Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid

1 reference

12 December 2020

Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine beta-synthase and A(2756)G of methionine synthase, with lowered plasma homocysteine levels.

1 reference

12 December 2020

Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

1 reference

12 December 2020

Linkage disequilibrium at the cystathionine β synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine

1 reference

12 December 2020

Effect of vitamin E on resistance vessel endothelial dysfunction induced by methionine

1 reference

12 December 2020

Effects of sex steroids on plasma total homocysteine levels: a study in transsexual males and females.

1 reference

12 December 2020

Effect of TCN2 776C>G on vitamin B12 cellular availability in end-stage renal disease patients

1 reference

12 December 2020

Gene-gene interaction between the cystathionine beta-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C > T polymorphism on homocysteine levels and risk for neural tube defects

1 reference

12 December 2020

Adverse event associated with methionine loading test: a case report

1 reference

12 December 2020

Single-nucleotide polymorphisms in genes relating to homocysteine metabolism: how applicable are public SNP databases to a typical European population?

1 reference

12 December 2020

Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice

1 reference

12 December 2020

The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

1 reference

12 December 2020

Human methylenetetrahydrofolate reductase: isolation of cDNA mapping and mutation identification.

1 reference

12 December 2020

Genetic modulation of homocysteinemia

1 reference

12 December 2020

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

1 reference

12 December 2020

Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.

1 reference

12 December 2020

p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma

1 reference

12 December 2020

The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study

1 reference

12 December 2020

Birth prevalence of homocystinuria

1 reference

12 December 2020

Relation between plasma homocysteine concentration, the 844ins68 variant of the cystathionine beta-synthase gene, and pyridoxal-5'-phosphate concentration.

1 reference

12 December 2020

Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease?

1 reference

12 December 2020

Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence

1 reference

12 December 2020

5,10-Methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations are genetic determinants of elevated homocysteine

1 reference

12 December 2020

Homocysteine species as components of plasma redox thiol status

1 reference

12 December 2020

Assignment of the gene for cystathionine beta-synthase to human chromosome 21 in somatic cell hybrids

1 reference

12 December 2020

Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients

1 reference

12 December 2020

Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism

1 reference

12 December 2020

Influence of 699C-->T and 1080C-->T polymorphisms of the cystathionine beta-synthase gene on plasma homocysteine levels.

1 reference

12 December 2020

Possible mechanisms of homocysteine toxicity.

1 reference

12 December 2020

Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency

1 reference

12 December 2020

Coronary heart disease mortality, plasma homocysteine, and B-vitamins: a prospective study

1 reference

12 December 2020

Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine

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12 December 2020

Renal homocysteine metabolism

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12 December 2020

Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine

1 reference

12 December 2020

Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction

1 reference

12 December 2020

Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994.

1 reference

12 December 2020

Intracellular S-adenosylhomocysteine increased levels are associated with DNA hypomethylation in HUVEC.

1 reference

12 December 2020

Net uptake of plasma homocysteine by the rat kidney in vivo

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12 December 2020

Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia

1 reference

12 December 2020

Plasma total homocysteine concentration and the risk of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Studytpdel

1 reference

12 December 2020

Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

1 reference

12 December 2020

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

1 reference

12 December 2020

Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization

1 reference

12 December 2020

Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

1 reference

12 December 2020

Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia.

1 reference

12 December 2020

Relation of serum homocysteine and lipoprotein(a) concentrations to atherosclerotic disease in a prospective Finnish population based study

1 reference

12 December 2020

Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria

1 reference

12 December 2020

Betaine-homocysteine methyltransferase (BHMT): genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans

1 reference

12 December 2020

Gene silencing. Methylation meets acetylation.

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12 December 2020

Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

1 reference

12 December 2020

Variable number tandem repeat in exon/intron border of the cystathionine beta-synthase gene: a single nucleotide substitution in the second repeat prevents multiple alternate splicing

1 reference

12 December 2020

Reduced, free and total fractions of homocysteine and other thiol compounds in plasma from patients with renal failure

1 reference

12 December 2020

Renal metabolism of homocysteine in vivo

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12 December 2020

Nutrition and aberrant DNA methylation patterns in atherosclerosis: more than just hyperhomocysteinemia?

1 reference

12 December 2020

The role of genetic factors in the development of hyperhomocysteinemia

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12 December 2020

The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

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12 December 2020

Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease

1 reference

12 December 2020

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

1 reference

12 December 2020

Superoxide-dependent cerebrovascular effects of homocysteine

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12 December 2020

A common 844INS68 insertion variant in the cystathionine beta-synthase gene

1 reference

12 December 2020

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

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12 December 2020

Effects of homocysteine on acetylcholine- and adenosine-induced vasodilatation of pancreatic vascular bed in rats

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12 December 2020

Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism

1 reference

12 December 2020

Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

1 reference

12 December 2020

Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

1 reference

12 December 2020

Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study.

1 reference

12 December 2020

Cystathionine beta-synthase deficiency in Central Europe: discrepancy between biochemical and molecular genetic screening for homocystinuric alleles.

1 reference

12 December 2020

Functional significance of G protein carboxymethylation

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12 December 2020

G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non homocysteine related mechanism

1 reference

12 December 2020

Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide

1 reference

12 December 2020

Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey.

1 reference

12 December 2020

Crystal structure of S-adenosylhomocysteine hydrolase from rat liver

1 reference

12 December 2020

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease

1 reference

12 December 2020

Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk

1 reference

12 December 2020

Transcobalamin polymorphism and homocysteine

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12 December 2020

DNA methylation and gene activity

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12 December 2020

Genetic determinants of the homocysteine level

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12 December 2020

A meta-analysis of cerebrovascular disease and hyperhomocysteinaemia

1 reference

12 December 2020

Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia.

1 reference

12 December 2020

Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects

1 reference

12 December 2020

Adverse effects of hyperhomocysteinemia and their management by folic acid

1 reference

12 December 2020

The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine

1 reference

12 December 2020

Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults

1 reference

12 December 2020

Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice

1 reference

12 December 2020

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

1 reference

12 December 2020

A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project

1 reference

12 December 2020

Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits.

1 reference

12 December 2020

The DNA methyltransferases of mammals

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12 December 2020

1 reference

12 December 2020

Folate-responsive homocystinuria and megaloblastic anaemia in a female patient with functional methionine synthase deficiency (cblE disease).

1 reference

12 December 2020

Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

1 reference

12 December 2020

Cellular import of cobalamin (Vitamin B-12).

1 reference

12 December 2020

Homocysteine metabolism in renal failure

1 reference

12 December 2020

A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia

1 reference

12 December 2020

Endothelial dysfunction by acute hyperhomocyst(e)inaemia: restoration by folic acid

1 reference

12 December 2020

Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels

1 reference

12 December 2020

Facts and recommendations about total homocysteine determinations: an expert opinion

1 reference

12 December 2020

Classical homocystinuria: vascular risk and its prevention

1 reference

12 December 2020

Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients.

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12 December 2020

Plasma homocysteine and menopausal status.

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12 December 2020

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

1 reference

12 December 2020

The metabolism of homocysteine: pathways and regulation

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12 December 2020

Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk

1 reference

12 December 2020

DNA methylation and atherosclerosis

1 reference

12 December 2020

Homocyst(e)ine and risk of cardiovascular disease in the Multiple Risk Factor Intervention Trial

1 reference

12 December 2020

10.1007/S10545-006-0106-5

Identifiers

DOI

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14 August 2017

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