The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase (Q38302392)

1 September 2017

The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase (English)

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1 September 2017

Vilkaitis G

1

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1 September 2017

Merkiene E

2

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1 September 2017

Serva S

3

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1 September 2017

Weinhold E

4

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1 September 2017

Klimasauskas S

5

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1 September 2017

language of work or name

English

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publication date

29 March 2001

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Journal of Biological Chemistry

1 September 2017

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1 September 2017

276

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1 September 2017

24

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1 September 2017

20924-20934

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HhaI methyltransferase flips its target base out of the DNA helix

1 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Purification, crystallization, and preliminary X-ray diffraction analysis of an M.HhaI-AdoMet complex.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Reconciling structure and function in HhaI DNA cytosine-C-5 methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Roles of Cys148 and Asp179 in catalysis by deoxycytidylate hydroxymethylase from bacteriophage T4 examined by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

2-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Chemical display of thymine residues flipped out by DNA methyltransferases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Dynamic modes of the flipped-out cytosine during HhaI methyltransferase-DNA interactions in solution.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

M.HhaI binds tightly to substrates containing mismatches at the target base

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Binding of the EcoRII methyltransferase to 5-fluorocytosine-containing DNA. Isolation of a bound peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

High level expression and purification of HhaI methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

The isotope trapping method: desorption rates of productive E.S complexes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Kinetics of methylation and binding of DNA by the EcoRV adenine-N6 methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

DNA distortion and base flipping by the EcoRV DNA methyltransferase. A study using interference at dA and T bases and modified deoxynucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Sequence-specific DNA binding by the MspI DNA methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101429200

Footprint analysis of M.Sssl and M.Hhal methyltransferases reveals extensive interactions with the substrate DNA backbone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Stereochemical studies of the C-methylation of deoxycytidine catalyzed by HhaI methylase and the N-methylation of deoxyadenosine catalyzed by EcoRI methylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Methylation of slipped duplexes, snapbacks and cruciforms by human DNA(cytosine-5)methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Mutation of asparagine 229 to aspartate in thymidylate synthase converts the enzyme to a deoxycytidylate methylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Kinetic mechanism of the EcoRI DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Pre-steady state kinetics of bacteriophage T4 dam DNA-[N(6)-adenine] methyltransferase: interaction with native (GATC) or modified sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Discrimination between DNA sequences by the EcoRV restriction endonuclease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Plasmid DNA Cleavage byMunI Restriction Enzyme: Single-Turnover and Steady-State Kinetic Analysis†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101429200

21 January 2018

Identifiers

DOI

10.1074/JBC.M101429200

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1 September 2017

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