Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform (Q36447899)

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6 January 2020

title

Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform (English)

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6 January 2020

3

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6 January 2020

author name string

Soochong Kim

series ordinal

1

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6 January 2020

Analia Garcia

series ordinal

2

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6 January 2020

Satya P Kunapuli

series ordinal

4

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6 January 2020

language of work or name

English

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publication date

7 September 2007

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6 January 2020

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6 January 2020

volume

110

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6 January 2020

issue

13

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6 January 2020

page(s)

4206-4213

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors

6 January 2020

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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

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Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

30 September 2017

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Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways

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Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2

30 September 2017

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30 September 2017

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30 September 2017

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ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

30 September 2017

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Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice

30 September 2017

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Signaling by distinct classes of phosphoinositide 3-kinases

30 September 2017

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Role of intracellular signaling events in ADP-induced platelet aggregation.

30 September 2017

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30 September 2017

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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

30 September 2017

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Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

30 September 2017

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Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

30 September 2017

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G protein beta gamma subunits.

30 September 2017

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p110δ, a novel phosphoinositide 3-kinase in leukocytes

30 September 2017

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

30 September 2017

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30 September 2017

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30 September 2017

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Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets

30 September 2017

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Purification and properties of an endothelial cell growth factor from human platelets

30 September 2017

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Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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28 June 2018

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

21 September 2018

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Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets

21 September 2018

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Akt Activation in Platelets Depends on Gi Signaling Pathways

21 September 2018

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Activation of Rap1B by G(i) family members in platelets

21 September 2018

1 reference

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21 September 2018

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A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase

21 September 2018

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12 December 2020

Dual regulation of platelet protein kinase B

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12 December 2020

ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of Galphaq

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12 December 2020

Somatomedin and platelet-derived growth factor in atherosclerosis

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12 December 2020

Demonstration of type I insulin-like growth factor receptors on human platelets

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12 December 2020

Human platelet-derived mitogens. I. Identification of insulinlike growth factors I and II by purification and N alpha amino acid sequence analysis

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12 December 2020

Human platelet-derived mitogens. II. Subcellular localization of insulinlike growth factor I to the alpha-granule and release in response to thrombin

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12 December 2020

Recombinant insulin-like growth factor-1 modulates aggregation in human platelets via extracellular calcium

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12 December 2020

Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation

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12 December 2020

The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro

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12 December 2020

10.1182/BLOOD-2007-03-080804

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17827385%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17827385%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

17827385

1 reference