Akt Activation in Platelets Depends on Gi Signaling Pathways (Q44659684)

5 December 2017

Akt activation in platelets depends on Gi signaling pathways (English)

1 reference

5 December 2017

Akt Activation in Platelets Depends on Gi Signaling Pathways (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

3 April 2024

author name string

Soochong Kim

1

1 reference

5 December 2017

Jianguo Jin

2

1 reference

5 December 2017

Satya P. Kunapuli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623889

3 April 2024

language of work or name

English

0 references

publication date

17 November 2003

1 reference

full work available at URL

5 December 2017

http://www.jbc.org/article/S0021925820749999/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623889

https://api.elsevier.com/content/article/PII:S0021925820749999?httpAccept=text/xml

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

https://api.elsevier.com/content/article/PII:S0021925820749999?httpAccept=text/plain

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

https://syndication.highwire.org/content/doi/10.1074/jbc.M306162200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Journal of Biological Chemistry

3 April 2024

published in

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5 December 2017

279

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5 December 2017

6

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5 December 2017

4186-4195

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

5 December 2017

1 reference

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 January 2018

1 reference

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Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin

21 January 2018

1 reference

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

21 January 2018

1 reference

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Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

21 January 2018

1 reference

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Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation

21 January 2018

1 reference

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Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Biphasic activation of PKBalpha/Akt in platelets. Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced via a novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Glycoprotein VI-mediated platelet fibrinogen receptor activation occurs through calcium-sensitive and PKC-sensitive pathways without a requirement for secreted ADP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Defective platelet activation in G alpha(q)-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Dual regulation of Akt/protein kinase B by heterotrimeric G protein subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Resistance to thromboembolism in PI3Kgamma-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306162200

Mechanism of activation of protein kinase B by insulin and IGF-1

21 January 2018

4

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Dual regulation of platelet protein kinase B

3 April 2024

6

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human platelets

3 April 2024

21

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy

3 April 2024

23

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Journal of Pharmacology and Experimental Therapeutics

3 April 2024

28

269

772

Savi

1994

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

3 April 2024

36

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Differential interaction of beta 1- and beta 3-adrenergic receptors with Gi in rat adipocytes

3 April 2024

38

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

3 April 2024

39

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

cAMP stimulates protein kinase B in a Wortmannin-insensitive manner

3 April 2024

40

1 reference

https://api.crossref.org/works/10.1074/JBC.M306162200

Platelet-Derived Growth Factor-BB and Thrombin Activate Phosphoinositide 3-Kinase and Protein Kinase B: Role in Mediating Airway Smooth Muscle Proliferation

3 April 2024

42

1 reference

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Phosphatidylinositol 3-kinase activity regulates alpha -thrombin-stimulated G1 progression by its effect on cyclin D1 expression and cyclin-dependent kinase 4 activity

3 April 2024

43

1 reference

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3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth

3 April 2024

47

1 reference

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PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat Adipocytes

3 April 2024

48

1 reference

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3 April 2024

Identifiers

1 reference

5 December 2017

1 reference