The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis (Q36451717)

14 August 2017

The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis (English)

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Mycobacterium tuberculosis

14 August 2017

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author

Luis Torre-Bouscoulet

object named as

Luis Torre-Bouscoulet

3

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Samuel M. Behar

object named as

Samuel M Behar

9

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author name string

Isabel Sada-Ovalle

1

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14 August 2017

Leslie Chávez-Galán

2

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14 August 2017

Lourdes Nava-Gamiño

4

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14 August 2017

Lourdes Barrera

5

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Pushpa Jayaraman

6

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14 August 2017

Martha Torres-Rojas

7

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Miguel Angel Salazar-Lezama

8

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14 August 2017

language of work or name

English

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publication date

23 November 2012

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14 August 2017

Journal of Immunology

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14 August 2017

189

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5896-5902

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12

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describes a project that uses

14 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3516679/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection

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Tim3 binding to galectin-9 stimulates antimicrobial immunity

30 September 2017

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T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

30 September 2017

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30 September 2017

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T-bet, a Th1 transcription factor regulates the expression of Tim-3.

30 September 2017

1 reference

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TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

30 September 2017

1 reference

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Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells

30 September 2017

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The costimulatory role of TIM molecules

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TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

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Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

30 September 2017

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Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria

30 September 2017

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Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

30 September 2017

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Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

30 September 2017

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Dysregulated T cell expression of TIM3 in multiple sclerosis

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Role of phagosomes and major histocompatibility complex class II (MHC-II) compartment in MHC-II antigen processing of Mycobacterium tuberculosis in human macrophages

30 September 2017

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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

30 September 2017

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Galectin-9 induces maturation of human monocyte-derived dendritic cells

30 September 2017

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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

30 September 2017

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T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis

30 September 2017

1 reference

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Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

30 September 2017

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Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.

30 September 2017

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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

30 September 2017

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Immunology of tuberculosis

30 September 2017

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30 September 2017

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Disseminated tuberculosis in interferon gamma gene-disrupted mice

30 September 2017

1 reference

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An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection

30 September 2017

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

30 September 2017

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TIMs: central regulators of immune responses

30 September 2017

1 reference

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Antigen-independent induction of Tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway

28 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516679

Elevated expression of Tim-3 on CD8 T cells correlates with disease severity of pulmonary tuberculosis.

21 September 2018

1 reference

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Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516679

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516679

Mycobacterium tuberculosis inhibits MHC class II antigen processing in murine bone marrow macrophages

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23180819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1200990

1 reference

14 August 2017

1 reference

14 August 2017

1 reference