Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes (Q36498294)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26733677%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes (English)

1 reference

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4 March 2020

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1 reference

6

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4 March 2020

author name string

Mingfeng Zhang

1

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4 March 2020

Qing Lin

2

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4 March 2020

Tong Qi

3

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4 March 2020

Tiankun Wang

4

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4 March 2020

Ching-Cheng Chen

5

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4 March 2020

Defu Zeng

7

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4 March 2020

language of work or name

English

0 references

publication date

5 January 2016

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

4 March 2020

published in

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4 March 2020

volume

113

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4 March 2020

issue

3

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4 March 2020

page(s)

650-655

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Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

4 March 2020

cites work

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Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells

30 September 2017

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Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial

30 September 2017

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30 September 2017

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30 September 2017

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Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

30 September 2017

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Islet β cell mass in diabetes and how it relates to function, birth, and death

30 September 2017

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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration

30 September 2017

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Concise review: pancreas regeneration: recent advances and perspectives

30 September 2017

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Progenitor cell domains in the developing and adult pancreas

30 September 2017

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The adult mouse and human pancreas contain rare multipotent stem cells that express insulin

30 September 2017

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Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas.

30 September 2017

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

30 September 2017

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Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

30 September 2017

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The clinical impact of islet transplantation

30 September 2017

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

30 September 2017

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

30 September 2017

1 reference

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

30 September 2017

1 reference

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Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

30 September 2017

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In vitro cultivation of human islets from expanded ductal tissue

30 September 2017

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Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas

30 September 2017

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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

30 September 2017

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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

30 September 2017

1 reference

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Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.

28 June 2018

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Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes

21 September 2018

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Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice

21 September 2018

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Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.

21 September 2018

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An Acidic pH and Activation of Phosphoinositide 3-Kinase Stimulate Differentiation of Pancreatic Progenitors Into Insulin-Producing Cells

21 September 2018

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21 September 2018

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Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

21 September 2018

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International trial of the Edmonton protocol for islet transplantation.

21 September 2018

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Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice

21 September 2018

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Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass

21 September 2018

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Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan

21 September 2018

1 reference

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Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes

21 September 2018

1 reference

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Lineage tracing of pancreatic stem cells and beta cell regeneration

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26733677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1524200113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26733677%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

1 reference

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4 March 2020

PubMed publication ID

26733677

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26733677%20AND%20SRC:MED&resulttype=core&format=json