Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes (Q47568710)

4 February 2018

title

Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes (English)

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4 February 2018

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Miao Wang

1

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4 February 2018

Jeremy J Racine

2

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4 February 2018

Xiaoping Song

3

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4 February 2018

Xiaofan Li

4

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4 February 2018

Indu Nair

5

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4 February 2018

Hongjun Liu

6

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4 February 2018

Alina Avakian-Mansoorian

7

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4 February 2018

Heather F Johnston

8

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4 February 2018

Can Liu

9

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4 February 2018

Christine Shen

10

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4 February 2018

Mark Atkinson

11

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4 February 2018

Ivan Todorov

12

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4 February 2018

Fouad Kandeel

13

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4 February 2018

Stephen Forman

14

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4 February 2018

Brian Wilson

15

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4 February 2018

Defu Zeng

16

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4 February 2018

language of work or name

English

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publication date

1 May 2012

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4 February 2018

Science Translational Medicine

published in

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4 February 2018

volume

4

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4 February 2018

issue

133

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4 February 2018

page(s)

133ra59

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4 February 2018

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

21 January 2018

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TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

21 January 2018

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Type 1 diabetes immunotherapy: is the glass half empty or half full?

21 January 2018

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Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice

21 January 2018

1 reference

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Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice

21 January 2018

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Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb.

21 January 2018

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Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes

21 January 2018

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Tolerance and chimerism after renal and hematopoietic-cell transplantation

21 January 2018

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 January 2018

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Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

21 January 2018

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

21 January 2018

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Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 January 2018

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

21 January 2018

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Generation of human islets through expansion and differentiation of non-islet pancreatic cells discarded (pancreatic discard) after islet isolation

21 January 2018

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Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.

21 January 2018

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Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass

21 January 2018

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Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice

21 January 2018

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HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen.

21 January 2018

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Hypothermia and hypoglycemia induced by anti-CD3 monoclonal antibody in mice: role of tumor necrosis factor.

21 January 2018

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Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin

21 January 2018

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Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan

21 January 2018

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Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM).

21 January 2018

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Increased vulnerability of newly forming beta cells to cytokine-induced cell death.

21 January 2018

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Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction

21 January 2018

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Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

21 January 2018

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Expression of gastrin and transforming growth factor-alpha during duct to islet cell differentiation in the pancreas of duct-ligated adult rats.

21 January 2018

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Current status of islet cell replacement and regeneration therapy

21 January 2018

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

21 January 2018

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10.1126/SCITRANSLMED.3003835

21 January 2018

Identifiers

DOI

1 reference

4 February 2018

release_nslhwdhzarhxxef6afjthtunae

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nslhwdhzarhxxef6afjthtunae

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22572882

1 reference

4 February 2018