Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance. (Q36498311)

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9 January 2020

title

Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance (English)

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9 January 2020

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4

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9 January 2020

author name string

Ting Wang

1

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9 January 2020

Xiaochao Ma

2

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9 January 2020

Kristopher W Krausz

3

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9 January 2020

Frank J Gonzalez

5

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9 January 2020

language of work or name

English

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publication date

25 October 2007

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Journal of Pharmacology and Experimental Therapeutics

9 January 2020

published in

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9 January 2020

volume

324

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9 January 2020

issue

2

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9 January 2020

page(s)

674-684

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Regulation of CYP26A1 expression by selective RAR and RXR agonists in human NB4 promyelocytic leukemia cells

9 January 2020

cites work

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Antibody binding capacity for evaluation of MDR-related proteins in acute promyelocytic leukemia: Onset versus relapse expression

30 September 2017

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The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

30 September 2017

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Retinoic acid resistance in acute promyelocytic leukemia

30 September 2017

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Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.

30 September 2017

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MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells

30 September 2017

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

30 September 2017

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

30 September 2017

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Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites

30 September 2017

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Biological activity of all-trans-retinoic acid with and without tamoxifen and alpha-interferon 2a in breast cancer patients

30 September 2017

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Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation

30 September 2017

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4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7

30 September 2017

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Retinoic acid: its biosynthesis and metabolism

30 September 2017

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

30 September 2017

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Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells

30 September 2017

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CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family

30 September 2017

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cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450

30 September 2017

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

30 September 2017

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Clinical characteristics, prognostic factors and multidrug-resistance related protein expression in 36 adult patients with acute promyelocytic leukemia.

30 September 2017

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Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia. The European APL Group.

28 June 2018

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All-trans retinoic acid in relapsing malignant gliomas: clinical and radiological stabilization associated with the appearance of intratumoral calcifications.

28 June 2018

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Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia

28 June 2018

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The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A.

28 June 2018

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Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia

21 September 2018

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A multicenter phase II study of the intravenous administration of liposomal tretinoin in patients with acquired immunodeficiency syndrome-associated Kaposi's sarcoma

21 September 2018

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Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor

21 September 2018

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21 September 2018

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Clinical pharmacology of oral all-trans retinoic acid in patients with acute promyelocytic leukemia.

21 September 2018

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Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

21 September 2018

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12 December 2020

Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes

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12 December 2020

Disposition of all-trans-retinoic acid in mice following oral doses

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12 December 2020

Analysis and stability of retinol in plasma

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12 December 2020

Mechanisms of retinoid resistance in leukemic cells: possible role of cytochrome P450 and P-glycoprotein

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12 December 2020

Restoration of retinoid sensitivity by MDR1 ribozymes in retinoic acid-resistant myeloid leukemic cells

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12 December 2020

Regulation of mRNA expression of xenobiotic transporters by the pregnane x receptor in mouse liver, kidney, and intestine

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12 December 2020

Identifiers

DOI

10.1124/JPET.107.131045

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962516%20AND%20SRC:MED&resulttype=core&format=json

release_ur45wemzorbofeep3qyhk4enui

9 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ur45wemzorbofeep3qyhk4enui

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962516%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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