Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis (Q36505836)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22450804%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis (English)

1 reference

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27 January 2020

1 reference

1 reference

3

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27 January 2020

Nicholas A Pullen

5

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27 January 2020

15

Sarah Spiegel

1 reference

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27 January 2020

16

Carole A Oskeritzian

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27 January 2020

author name string

Yves T Falanga

1

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27 January 2020

Natalia S Chaimowitz

2

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27 January 2020

Fred D Finkelman

4

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27 January 2020

Suzanne Barbour

6

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27 January 2020

Kevin Dholaria

7

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27 January 2020

Travis Faber

8

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27 January 2020

Motunrayo Kolawole

9

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27 January 2020

Bernice Huang

10

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27 January 2020

Sandra Odom

11

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27 January 2020

Juan Rivera

12

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27 January 2020

Jason Carlyon

13

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27 January 2020

Daniel H Conrad

14

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27 January 2020

John J Ryan

17

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27 January 2020

language of work or name

English

0 references

publication date

26 March 2012

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27 January 2020

published in

Journal of Immunology

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27 January 2020

volume

188

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27 January 2020

issue

9

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27 January 2020

page(s)

4360-4368

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Mouse and human neutrophils induce anaphylaxis.

27 January 2020

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The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells

30 September 2017

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Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation

30 September 2017

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Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation

30 September 2017

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The tyrosine kinase network regulating mast cell activation

30 September 2017

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New insights into the roles for basophils in acute and chronic allergy

30 September 2017

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Newly discovered roles for basophils: a neglected minority gains new respect.

30 September 2017

1 reference

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New developments in mast cell biology

30 September 2017

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Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis

30 September 2017

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New insights on mast cell activation via the high affinity receptor for IgE

30 September 2017

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30 September 2017

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Immunomodulatory mast cells: negative, as well as positive, regulators of immunity

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30 September 2017

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A current understanding of Fc epsilon RI-dependent mast cell activation

30 September 2017

1 reference

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Fcgamma receptors as regulators of immune responses

30 September 2017

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Anaphylaxis: lessons from mouse models

30 September 2017

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Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation.

30 September 2017

1 reference

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An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response

30 September 2017

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Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells

30 September 2017

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Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI

30 September 2017

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Lyn tyrosine kinase: accentuating the positive and the negative

30 September 2017

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30 September 2017

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Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL

30 September 2017

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Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase

30 September 2017

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Regulation of gene expression in mouse macrophages stimulated with bacterial CpG-DNA and lipopolysaccharide.

30 September 2017

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Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

30 September 2017

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Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.

30 September 2017

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Akt-dependent cytokine production in mast cells

30 September 2017

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

30 September 2017

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Mechanisms of phagocytosis in macrophages

30 September 2017

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Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG.

30 September 2017

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Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways

30 September 2017

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A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals

30 September 2017

1 reference

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A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

30 September 2017

1 reference

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Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains

30 September 2017

1 reference

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Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis

30 September 2017

1 reference

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Human type II Fcgamma receptors inhibit B cell activation by interacting with the p21(ras)-dependent pathway

30 September 2017

1 reference

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Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice

30 September 2017

1 reference

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Connective tissue proteins and phagocytic cell function. Laminin enhances complement and Fc-mediated phagocytosis by cultured human macrophages

30 September 2017

1 reference

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Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice

30 September 2017

1 reference

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Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus

30 September 2017

1 reference

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Alternatively spliced murine lyn mRNAs encode distinct proteins

30 September 2017

1 reference

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Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

30 September 2017

1 reference

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Murine recombinant Fc gamma RIII, but not Fc gamma RII, trigger serotonin release in rat basophilic leukemia cells.

30 September 2017

1 reference

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Clinical correlations between long-term (IgE) and short-term (IgG S-TS) anaphylactic antibodies in atopic and 'non-atopic' subjects with respiratory allergic disease

30 September 2017

1 reference

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Platelet-activating factor induces the tyrosine phosphorylation and activation of phospholipase C-gamma 1, Fyn and Lyn kinases, and phosphatidylinositol 3-kinase in a human B cell line.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene.

28 June 2018

1 reference

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IgG subclasses in bronchoalveolar lavage fluid from patients with asthma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Peanuts can contribute to anaphylactic shock by activating complement.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Basophils now enhance memory.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Impaired FcepsilonRI-dependent gene expression and defective eicosanoid and cytokine production as a consequence of Fyn deficiency in mast cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Differential expression of platelet-activating factor acetylhydrolase in macrophages and monocyte-derived dendritic cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Pathways of anaphylaxis in the mouse

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536057

Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

21 September 2018

1 reference

12 December 2020

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1 reference

12 December 2020

Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells

1 reference

12 December 2020

Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus

1 reference

12 December 2020

Basophils are essential initiators of a novel type of chronic allergic inflammation

1 reference

12 December 2020

Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells

1 reference

12 December 2020

Syk-deficient eosinophils show normal interleukin-5-mediated differentiation, maturation, and survival but no longer respond to FcgammaR activation

1 reference

12 December 2020

B-cell kinase lyn deficiency in patients with systemic lupus erythematosus

1 reference

12 December 2020

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1003223

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22450804%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22450804%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22450804%20AND%20SRC:MED&resulttype=core&format=json