Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation. (Q36506062)

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scientific article published on 31 October 2012

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English	Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.	scientific article published on 31 October 2012

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scholarly article

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16 February 2020

Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation (English)

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16 February 2020

attenuated vaccine

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based on heuristic

inferred from title

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based on heuristic

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Francisella tularensis

object named as

Francisella tularensis

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based on heuristic

inferred from title

1

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16 February 2020

Blake W. Buchan

3

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16 February 2020

6

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16 February 2020

author name string

Ann M Janowski

2

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16 February 2020

Matthew Faron

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16 February 2020

Suzanne L Cassel

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16 February 2020

Fayyaz S Sutterwala

7

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16 February 2020

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publication date

31 October 2012

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16 February 2020

Infection and Immunity

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16 February 2020

81

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16 February 2020

1

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16 February 2020

201-208

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Europe PubMed Central

PMC publication ID

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16 February 2020

Sensing damage by the NLRP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis

1 reference

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30 September 2017

A galU mutant of Francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis

1 reference

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30 September 2017

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.

1 reference

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30 September 2017

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence.

1 reference

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30 September 2017

Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Sensing pathogens and danger signals by the inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

The Nalp3 inflammasome is essential for the development of silicosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Identification of differentially regulated francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Substrate specificity of the pseudouridine synthase RluD in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Toll-like receptor 2 controls the gamma interferon response to Francisella tularensis by mouse liver lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages

1 reference

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30 September 2017

In vivo negative selection screen identifies genes required for Francisella virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

1 reference

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30 September 2017

Francisella tularensis: taxonomy, genetics, and Immunopathogenesis of a potential agent of biowarfare

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536133

30 September 2017

Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release

1 reference

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30 September 2017

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

1 reference

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30 September 2017

Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages

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30 September 2017

EVALUATION OF LIVE TULAREMIA VACCINE PREPARED IN A CHEMICALLY DEFINED MEDIUM.

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30 September 2017

Virulence determinants and protective antigens of Francisella tularensis.

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30 September 2017

Selective suppression of interleukin-12 induction after macrophage receptor ligation

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30 September 2017

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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30 September 2017

Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence

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28 June 2018

Defective NK cell activity and Th1 response in IL-18-deficient mice

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28 June 2018

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

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21 September 2018

Investigations of the roles of arginine 115 and lysine 120 in the active site of 5,10-methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae.

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21 September 2018

The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli

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Purification and properties of 5,10-methenyltetrahydrofolate synthetase from Lactobacillus casei

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12 December 2020

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Phenotypic and functional characterization of mice that lack the type I receptor for IL-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23115038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tularemia vaccine study. II. Respiratory challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/23115038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tularemia vaccine study. I. Intracutaneous challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/23115038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.00991-12

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Europe PubMed Central

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16 February 2020

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16 February 2020

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16 February 2020

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