Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity (Q36507525)

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scientific article published on 15 January 2016

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English	Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity	scientific article published on 15 January 2016

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity (English)

1 reference

Europe PubMed Central

14 August 2017

Louise Deldicque

7

object named as

Louise Deldicque

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3

object named as

Damien Naslain

0 references

1

object named as

Marc Francaux

0 references

author name string

Bénédicte Demeulder

2

1 reference

Europe PubMed Central

14 August 2017

Raphael Fortin

4

1 reference

Europe PubMed Central

14 August 2017

Olivier Lutz

5

1 reference

Europe PubMed Central

14 August 2017

Gilles Caty

6

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Europe PubMed Central

14 August 2017

publication date

15 January 2016

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Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

8

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Europe PubMed Central

14 August 2017

1

1 reference

Europe PubMed Central

14 August 2017

copyright license

Creative Commons Attribution 4.0 International

15 January 2016

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April 2022 Public Data File from Crossref

copyright status

0 references

Aberrant REDD1-mTORC1 responses to insulin in skeletal muscle from Type 2 diabetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

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Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014.

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Biochemical artifacts in experiments involving repeated biopsies in the same muscle

1 reference

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30 September 2017

A role for Raptor phosphorylation in the mechanical activation of mTOR signaling.

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30 September 2017

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

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Targeting anabolic impairment in response to resistance exercise in older adults with mobility impairments: potential mechanisms and rehabilitation approaches.

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Interactions between exercise and nutrition to prevent muscle waste during ageing

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Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

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Role of PRAS40 in Akt and mTOR signaling in health and disease.

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Isoleucine and leucine independently regulate mTOR signaling and protein synthesis in MAC-T cells and bovine mammary tissue slices.

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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

The anabolic response to resistance exercise and a protein-rich meal is not diminished by age.

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30 September 2017

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

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30 September 2017

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

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30 September 2017

Autophagy: assays and artifacts

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30 September 2017

Autophagy in skeletal muscle

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans

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30 September 2017

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy

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30 September 2017

Molecular mechanisms of mTOR-mediated translational control

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

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30 September 2017

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Autophagy revisited: a conversation with Christian de Duve

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

AMPK phosphorylation of raptor mediates a metabolic checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

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Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

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Maintenance of the musculoskeletal mass by control of protein turnover: the concept of anabolic resistance and its relevance to the transplant recipient.

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30 September 2017

Insulin resistance of muscle protein metabolism in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

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Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

1 reference

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REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

1 reference

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

1 reference

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30 September 2017

Control of protein synthesis by amino acid availability

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men.

1 reference

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28 June 2018

Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

28 June 2018

The muscle protein synthetic response to the combined ingestion of protein and carbohydrate is not impaired in healthy older men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Blunting of adaptive responses to resistance exercise training in women over 75y.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Protein anabolic responses to a fed steady state in healthy aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Exercising before protein intake allows for greater use of dietary protein-derived amino acids for de novo muscle protein synthesis in both young and elderly men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Anabolic resistance: the effects of aging, sexual dimorphism, and immobilization on human muscle protein turnover.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Effects of increasing insulin secretion on acute postexercise blood glucose disposal.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Does hypoxia cause sarcopenia? Prevention of hypoxia could reduce sarcopenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

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Proteolytic gene expression differs at rest and after resistance exercise between young and old women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

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inferred from PubMed ID database lookup

Splanchnic and whole-body leucine kinetics in young and elderly men

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

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inferred from PubMed ID database lookup

Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

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based on heuristic

inferred from PubMed ID database lookup

Activation of mTOR signalling in young and old human skeletal muscle in response to combined resistance exercise and whey protein ingestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU8010047

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Europe PubMed Central

14 August 2017

release_a7x7xlc6ybdhjdwc72hv3mxyfu

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https://api.fatcat.wiki/v0/release/a7x7xlc6ybdhjdwc72hv3mxyfu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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