REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. (Q34375626)

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6 January 2020

title

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase (English)

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6 January 2020

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1

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6 January 2020

author name string

Daniel Tondera

2

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6 January 2020

Wolfgang Arnold

3

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6 January 2020

Klaus Giese

4

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6 January 2020

Anke Klippel

5

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6 January 2020

Jörg Kaufmann

6

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6 January 2020

language of work or name

English

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publication date

1 February 2005

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6 January 2020

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6 January 2020

volume

24

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6 January 2020

page(s)

1138-1149

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6 January 2020

issue

7

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208236

6 January 2020

exact match

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cites work

Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

1 reference

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Tumor cell hypoxia and the hypoxia-response signaling system as a target for prostate cancer therapy

21 January 2018

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Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

21 January 2018

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

21 January 2018

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

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Inducible shRNA expression for application in a prostate cancer mouse model

21 January 2018

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HIF at the crossroads between ischemia and carcinogenesis

21 January 2018

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Hypoxia and CoCl2 protect HepG2 cells against serum deprivation- and t-BHP-induced apoptosis: a possible anti-apoptotic role for HIF-1.

21 January 2018

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HIF-1 and hypoxic response: the plot thickens.

21 January 2018

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Modeling tissue-specific signaling and organ function in three dimensions

21 January 2018

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PTEN: life as a tumor suppressor

21 January 2018

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Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis

21 January 2018

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Signaling by distinct classes of phosphoinositide 3-kinases

21 January 2018

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Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha

21 January 2018

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PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

21 January 2018

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Role of redox potential and reactive oxygen species in stress signaling

21 January 2018

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7 January 2021

Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

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7 January 2021

The hypoxic response of tumors is dependent on their microenvironment.

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7 January 2021

Out of air is not out of action

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7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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7 January 2021

Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.

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7 January 2021

The multiple roles of PTEN in tumor suppression

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7 January 2021

Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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7 January 2021

Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4

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7 January 2021

CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2.

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7 January 2021

Is HIF-1alpha a pro- or an anti-apoptotic protein?

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7 January 2021

Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways

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7 January 2021

Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

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7 January 2021

Metastatic model for human prostate cancer using orthotopic implantation in nude mice

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7 January 2021

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592522%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

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