Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. (Q36515439)

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5 March 2020

title

Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer (English)

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5 March 2020

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5

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5 March 2020

Ronny Drapkin

8

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David M Weinstock

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5 March 2020

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Ursula Matulonis

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5 March 2020

author name string

Young Eun Choi

1

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5 March 2020

Khyati Meghani

2

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Marie-Eve Brault

3

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5 March 2020

Lucas Leclerc

4

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5 March 2020

Tovah A Day

6

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5 March 2020

Kevin M Elias

7

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5 March 2020

Fanny Dao

10

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5 March 2020

Karin K Shih

11

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5 March 2020

Douglas A Levine

13

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5 March 2020

Panagiotis A Konstantinopoulos

14

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Dipanjan Chowdhury

15

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publication date

7 January 2016

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5 March 2020

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5 March 2020

volume

14

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5 March 2020

issue

3

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5 March 2020

page(s)

429-439

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Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer

5 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers

30 September 2017

1 reference

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REV7 counteracts DNA double-strand break resection and affects PARP inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage.

30 September 2017

1 reference

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A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice

30 September 2017

1 reference

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Playing the end game: DNA double-strand break repair pathway choice

30 September 2017

1 reference

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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Integrated genomic analyses of ovarian carcinoma

30 September 2017

1 reference

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Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.

30 September 2017

1 reference

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A microRNA survival signature (MiSS) for advanced ovarian cancer.

30 September 2017

1 reference

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miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

The DNA Damage Response: Making It Safe to Play with Knives

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731274

miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements

30 September 2017

1 reference

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

30 September 2017

1 reference

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Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

30 September 2017

1 reference

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Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

30 September 2017

1 reference

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Isolation of microRNA targets using biotinylated synthetic microRNAs.

30 September 2017

1 reference

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Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions

30 September 2017

1 reference

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The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle

30 September 2017

1 reference

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The Ku heterodimer and the metabolism of single-ended DNA double-strand breaks

28 June 2018

1 reference

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10.1016/J.CELREP.2015.12.046

21 September 2018

Identifiers

DOI

1 reference

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5 March 2020

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5 March 2020

PubMed publication ID

26774475

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