Systems Biology Approaches and Applications in Obesity, Diabetes, and Cardiovascular Diseases (Q36527837)

14 August 2017

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title

Systems Biology Approaches and Applications in Obesity, Diabetes, and Cardiovascular Diseases (English)

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14 August 2017

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cardiovascular disease

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inferred from title

author

Ville-Petteri Mäkinen

object named as

Ville-Petteri Mäkinen

2

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author name string

Qingying Meng

1

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14 August 2017

Helen Luk

3

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14 August 2017

Xia Yang

4

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14 August 2017

language of work or name

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18 October 2012

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Journal of Cardiovascular Risk

14 August 2017

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14 August 2017

7

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1

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73-83

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describes a project that uses

14 August 2017

WGCNA

object named as

WGCNA

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1007/s12170-012-0280-y

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cites work

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Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes

30 September 2017

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Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes

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30 September 2017

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Functional proteomics: application of mass spectrometry to the study of enzymology in complex mixtures

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Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

30 September 2017

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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

30 September 2017

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30 September 2017

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Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension

30 September 2017

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

30 September 2017

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Gene co-expression modules and type 2 diabetes

30 September 2017

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Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Genomewide association studies and assessment of the risk of disease

30 September 2017

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Epigenetics and cardiovascular disease

30 September 2017

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

30 September 2017

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Identification and validation of genes affecting aortic lesions in mice

30 September 2017

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Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

30 September 2017

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Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes

30 September 2017

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Expression quantitative trait loci: replication, tissue- and sex-specificity in mice

30 September 2017

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Identifying essential genes in bacterial metabolic networks with machine learning methods

30 September 2017

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Integrating pathway analysis and genetics of gene expression for genome-wide association studies

30 September 2017

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Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice

30 September 2017

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Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases

30 September 2017

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Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications

30 September 2017

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30 September 2017

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eQTL analysis in mice and rats

30 September 2017

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Disease signatures are robust across tissues and experiments

30 September 2017

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A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia

30 September 2017

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Common body mass index-associated variants confer risk of extreme obesity

30 September 2017

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

30 September 2017

1 reference

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Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

30 September 2017

1 reference

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

30 September 2017

1 reference

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WGCNA: an R package for weighted correlation network analysis

30 September 2017

1 reference

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Personal genomes: The case of the missing heritability

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Metabolic syndrome: from epidemiology to systems biology

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

30 September 2017

1 reference

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Weighted lasso in graphical Gaussian modeling for large gene network estimation based on microarray data.

30 September 2017

1 reference

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Mapping the genetic architecture of gene expression in human liver

30 September 2017

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A systems biology approach to drug discovery

30 September 2017

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A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

30 September 2017

1 reference

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Variations in DNA elucidate molecular networks that cause disease

30 September 2017

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Genetics of gene expression and its effect on disease

30 September 2017

1 reference

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Eigengene networks for studying the relationships between co-expression modules

30 September 2017

1 reference

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AILUN: reannotating gene expression data automatically

30 September 2017

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Evaluation and integration of 49 genome-wide experiments and the prediction of previously unknown obesity-related genes

30 September 2017

1 reference

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Weighted gene coexpression network analysis strategies applied to mouse weight

30 September 2017

1 reference

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Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics

30 September 2017

1 reference

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Finding disease-related genomic experiments within an international repository: first steps in translational bioinformatics

30 September 2017

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Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

30 September 2017

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Integrating genetic and network analysis to characterize genes related to mouse weight

30 September 2017

1 reference

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Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids

30 September 2017

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ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

30 September 2017

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A general framework for weighted gene co-expression network analysis

30 September 2017

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Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity

30 September 2017

1 reference

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Creation and implications of a phenome-genome network

30 September 2017

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An integrative genomics approach to infer causal associations between gene expression and disease

30 September 2017

1 reference

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Bayesian network analysis of signaling networks: a primer

30 September 2017

1 reference

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Network biology: understanding the cell's functional organization

30 September 2017

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A Bayesian Networks Approach for Predicting Protein-Protein Interactions from Genomic Data

30 September 2017

1 reference

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Comparison and meta-analysis of microarray data: from the bench to the computer desk.

30 September 2017

1 reference

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‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

30 September 2017

1 reference

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Genetics of gene expression surveyed in maize, mouse and man

30 September 2017

1 reference

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Hierarchical organization of modularity in metabolic networks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Using Bayesian networks to analyze expression data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Genome scan for human obesity and linkage to markers in 20q13.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Inference of a genetic network by a combined approach of cluster analysis and graphical Gaussian modeling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Mapping of the human insulin receptor substrate-2 gene, identification of a linked polymorphic marker and linkage analysis in families with Type II diabetes: no evidence for a major susceptibility role.

28 June 2018

1 reference

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A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice

21 September 2018

1 reference

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Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

An empirical Bayes approach to inferring large-scale gene association networks.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

An integrative genomics approach to the reconstruction of gene networks in segregating populations.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Meta-analysis of 4 coronary heart disease genome-wide linkage studies confirms a susceptibility locus on chromosome 3q.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

Inferring subnetworks from perturbed expression profiles

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3543610

An immune response network associated with blood lipid levels

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12170-012-0280-Y

A probabilistic functional network of yeast genes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23326608

12 December 2020

inferred from PubMed ID database lookup

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23326608

12 December 2020

inferred from PubMed ID database lookup

Genome-wide association studies and systems biology: together at last

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23326608

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S12170-012-0280-Y

1 reference

14 August 2017

1 reference

14 August 2017

1 reference