Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor (Q36532748)

14 August 2017

Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor (English)

1 reference

14 August 2017

Shun Matsuda

1

1 reference

14 August 2017

Jun Adachi

2

1 reference

14 August 2017

Masaru Ihara

3

1 reference

14 August 2017

Nobuhiro Tanuma

4

1 reference

14 August 2017

Hiroshi Shima

5

1 reference

14 August 2017

Akira Kakizuka

6

1 reference

14 August 2017

Masae Ikura

7

1 reference

14 August 2017

Tsuyoshi Ikura

8

1 reference

14 August 2017

Tomonari Matsuda

9

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14 August 2017

language of work or name

English

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publication date

23 September 2015

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14 August 2017

Nucleic Acids Research

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14 August 2017

44

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14 August 2017

2

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14 August 2017

636-647

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Creative Commons Attribution 4.0 International

14 August 2017

start time

11 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation

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PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

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Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells

30 September 2017

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

30 September 2017

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Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

30 September 2017

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Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

30 September 2017

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Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription.

30 September 2017

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Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones

30 September 2017

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ATP-citrate lyase links cellular metabolism to histone acetylation

30 September 2017

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Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.

30 September 2017

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

30 September 2017

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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

30 September 2017

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Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription

30 September 2017

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Pyruvate kinase type M2 and its role in tumor growth and spreading

30 September 2017

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Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin

30 September 2017

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CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

30 September 2017

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Regulation of glycolysis by Raf protein serine/threonine kinases

30 September 2017

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Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

30 September 2017

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Effects of histone deacetylase inhibitors on the Ah receptor gene promoter

30 September 2017

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Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

30 September 2017

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Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

30 September 2017

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Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice

30 September 2017

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CBP/p300 functions as a possible transcriptional coactivator of Ah receptor nuclear translocator (Arnt).

30 September 2017

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2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

30 September 2017

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The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

30 September 2017

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Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs).

30 September 2017

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A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.

30 September 2017

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Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

30 September 2017

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Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation

30 September 2017

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Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA.

30 September 2017

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Evidence that core histone H3 is targeted to the mitochondria in Brassica oleracea.

21 September 2018

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Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737187

An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates

21 September 2018

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12 December 2020

Pyruvate kinase isoenzyme transitions in cultures of fetal rat hepatocytes

1 reference

12 December 2020

Temporally distinctive changes of alternative splicing patterns during myogenic differentiation of C2C12 cells

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12 December 2020

Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands

1 reference

12 December 2020

Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKV967

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26405201

1 reference