Dendritic cells, regulatory T cells and the pathogenesis of chronic hepatitis C. (Q36535789)

14 August 2017

16 references

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3 November 2019

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Dendritic cells, regulatory T cells and the pathogenesis of chronic hepatitis C. (English)

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evasion of host immune response

14 August 2017

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hemic and immune systems

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host microbial interaction

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27 July 2020

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1 November 2020

22 August 2022

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26 October 2022

3

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14 August 2017

7

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14 August 2017

610-620

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Creative Commons Attribution-NonCommercial 3.0 Unported

14 August 2017

17 references

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3 August 2019

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25 September 2019

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3 November 2019

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Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

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The battle against immunopathology: infectious tolerance mediated by regulatory T cells

30 September 2017

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Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions

30 September 2017

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The affect of chronic hepatitis C infection on dendritic cell function: a summary of the experimental evidence.

30 September 2017

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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

30 September 2017

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Dendritic cells in hepatitis C infection: can they (help) win the battle?

30 September 2017

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Human FoxP3(+)CD4(+) regulatory T cells: their knowns and unknowns

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Plasmacytoid dendritic cells: recent progress and open questions

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Hepatitis C virus induces regulatory T cells by naturally occurring viral variants to suppress T cell responses

30 September 2017

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How tolerogenic dendritic cells induce regulatory T cells

30 September 2017

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Preserved MHC-II antigen processing and presentation function in chronic HCV infection

30 September 2017

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Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link

30 September 2017

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FOXP3+ regulatory T cells in the human immune system

30 September 2017

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Immunomodulation by hepatitis C virus-derived proteins: targeting human dendritic cells by multiple mechanisms

30 September 2017

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Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.

30 September 2017

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Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection

30 September 2017

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Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection

30 September 2017

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Host genetic determinants of spontaneous hepatitis C clearance

30 September 2017

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Immune tolerance: what is unique about the liver

30 September 2017

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Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

30 September 2017

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Mechanisms of foxp3+ T regulatory cell-mediated suppression

30 September 2017

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Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

30 September 2017

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Regulatory T cells in the control of host-microorganism interactions (*).

30 September 2017

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The divergence and interplay between pDC and mDC in humans

30 September 2017

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Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

30 September 2017

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Human liver dendritic cells promote T cell hyporesponsiveness

30 September 2017

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Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes

30 September 2017

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Plasmacytoid dendritic cells move down on the list of suspects: in search of the immune pathogenesis of chronic hepatitis C.

30 September 2017

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CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner

30 September 2017

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How regulatory T cells work

30 September 2017

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30 September 2017

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Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II.

30 September 2017

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Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection

30 September 2017

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

30 September 2017

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Hepatitis C Virus Inhibits Cell Surface Expression of HLA-DR, Prevents Dendritic Cell Maturation, and Induces Interleukin-10 Production

30 September 2017

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Monocyte derived dendritic cells retain their functional capacity in patients following infection with hepatitis C virus

30 September 2017

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Peripheral blood dendritic cells are phenotypically and functionally intact in chronic hepatitis B virus (HBV) infection

30 September 2017

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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

30 September 2017

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Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

30 September 2017

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30 September 2017

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Genetic diversity of the hepatitis C virus: impact and issues in the antiviral therapy

30 September 2017

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

30 September 2017

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

30 September 2017

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Natural regulatory T cells: mechanisms of suppression

30 September 2017

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Differential dysfunction in dendritic cell subsets during chronic HCV infection.

30 September 2017

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The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression

30 September 2017

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CD4+CD25+ Tregs and NKT cells: regulators regulating regulators

30 September 2017

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Activated CD4+CD25+ T cells selectively kill B lymphocytes

30 September 2017

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Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins

30 September 2017

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Plasmacytoid dendritic cells--virus experts of innate immunity

30 September 2017

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Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

30 September 2017

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T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

30 September 2017

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Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection

30 September 2017

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IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

30 September 2017

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Plasmacytoid dendritic cells in immunity

30 September 2017

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Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation

30 September 2017

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Role of LAG-3 in regulatory T cells.

30 September 2017

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Direct enumeration and functional assessment of circulating dendritic cells in patients with liver disease.

30 September 2017

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Decreased interferon-alpha production and impaired T helper 1 polarization by dendritic cells from patients with chronic hepatitis C

30 September 2017

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Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation

30 September 2017

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Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus

30 September 2017

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Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

30 September 2017

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Natural versus adaptive regulatory T cells

30 September 2017

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Tolerogenic dendritic cells

30 September 2017

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

30 September 2017

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Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

30 September 2017

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Hepatocellular carcinoma and hepatitis C in the United States

30 September 2017

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Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

30 September 2017

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Phenotypic analysis of circulating and intrahepatic dendritic cell subsets in patients with chronic liver diseases

30 September 2017

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Mouse and human dendritic cell subtypes

30 September 2017

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

30 September 2017

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

30 September 2017

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BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood

30 September 2017

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Chemokines and dendritic cell traffic.

30 September 2017

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Analysis of successful immune responses in persons infected with hepatitis C virus

30 September 2017

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Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

30 September 2017

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Dendritic cells and the control of immunity

30 September 2017

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Expression and identification of hepatitis C virus polyprotein cleavage products

30 September 2017

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

30 September 2017

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The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team

30 September 2017

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Hepatitis C virus NS4 protein impairs the Th1 polarization of immature dendritic cells

30 September 2017

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Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition

28 June 2018

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Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

28 June 2018

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

28 June 2018

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An autoantibody cross-reactive to hepatitis C virus core and a host nuclear antigen

28 June 2018

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IL28B genetic variants and gender are associated with spontaneous clearance of hepatitis C virus infection

28 June 2018

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Up-regulation of FOXP3 and induction of suppressive function in CD4+ Jurkat T-cells expressing hepatitis C virus core protein

21 September 2018

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Functional impairment of dendritic cells in patients infected with hepatitis C virus genotype 1 who failed peginterferon plus ribavirin therapy

21 September 2018

1 reference

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Human dendritic cells expressing hepatitis C virus core protein display transcriptional and functional changes consistent with maturation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Early viraemia clearance during antiviral therapy of chronic hepatitis C improves dendritic cell functions

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Myeloid dendritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Decreased interferon-alpha production and impaired regulatory function of plasmacytoid dendritic cells induced by the hepatitis C virus NS 5 protein

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Decrease and dysfunction of dendritic cells correlate with impaired hepatitis C virus-specific CD4+ T-cell proliferation in patients with hepatitis C virus infection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Defining target antigens for CD25+ FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Plasmacytoid dendritic cells in acute and chronic hepatitis C virus infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Clearance of hepatitis C virus after newly acquired infection in injection drug users

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Selective impairments in dendritic cell-associated function distinguish hepatitis C virus and HIV infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Scope of worldwide hepatitis C problem

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Detection of functionally altered hepatitis C virus-specific CD4+ T cells in acute and chronic hepatitis C

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Mobilizing dendritic cells for tolerance, priming, and chronic inflammation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: enrichment for Valpha24+ T cells and rapid elimination of effector cells by apoptosis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545943

Altered chemotactic response of myeloid and plasmacytoid dendritic cells from patients with chronic hepatitis C: role of alpha interferon

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FVIRU.21823

Comparable functions of plasmacytoid and monocyte-derived dendritic cells in chronic hepatitis C patients and healthy donors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FVIRU.21823

Early activation markers of human peripheral dendritic cells

21 January 2018

1 reference

12 December 2020

Monocyte-derived dendritic cell function in chronic hepatitis C is impaired at physiological numbers of dendritic cells

1 reference

12 December 2020

Estimating future hepatitis C morbidity, mortality, and costs in the United States

1 reference

12 December 2020

Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking

1 reference

12 December 2020

Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C

1 reference

12 December 2020

Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature

1 reference

12 December 2020

The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation

1 reference

12 December 2020

Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells

1 reference

12 December 2020

Core-specific adaptive regulatory T-cells in different outcomes of hepatitis C

1 reference

12 December 2020

[Protective role of HLA-B27 in HIV and hepatitis C virus infection]

1 reference

12 December 2020

Identifiers

DOI

10.4161/VIRU.21823

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23076334

1 reference