Rad50S alleles of the Mre11 complex: questions answered and questions raised (Q36542150)

14 August 2017

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title

Rad50S alleles of the Mre11 complex: questions answered and questions raised (English)

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14 August 2017

2

John H J Petrini

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14 August 2017

Takehiko Usui

1

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14 August 2017

Monica Morales

series ordinal

3

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14 August 2017

language of work or name

English

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publication date

20 June 2006

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Experimental Cell Research

14 August 2017

published in

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14 August 2017

volume

312

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14 August 2017

issue

14

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14 August 2017

page(s)

2694-2699

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The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

14 August 2017

cites work

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Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

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Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

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Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

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Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

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Meiotic cells monitor the status of the interhomolog recombination complex

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Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

7 January 2021

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

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A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis

7 January 2021

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Complex formation and functional versatility of Mre11 of budding yeast in recombination

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hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

7 January 2021

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Nbs1 is required for ATR-dependent phosphorylation events

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Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway.

7 January 2021

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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

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Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

7 January 2021

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Dissecting p53 tumor suppressor functions in vivo

7 January 2021

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Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

7 January 2021

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The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

7 January 2021

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Endonucleolytic processing of covalent protein-linked DNA double-strand breaks

7 January 2021

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Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

7 January 2021

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Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage

7 January 2021

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Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I.

7 January 2021

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7 January 2021

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Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

7 January 2021

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S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

7 January 2021

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The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons

7 January 2021

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An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

7 January 2021

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Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast

7 January 2021

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Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae

7 January 2021

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

7 January 2021

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Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells

7 January 2021

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Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints

7 January 2021

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Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11.

7 January 2021

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The mouse Spo11 gene is required for meiotic chromosome synapsis

7 January 2021

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A DNA damage response pathway controlled by Tel1 and the Mre11 complex

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.06.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YEXCR.2006.06.013

1 reference

14 August 2017

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