The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons (Q28306393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699047%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons (English)

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8 January 2020

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Karen Flatten

1

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8 January 2020

Nga T Dai

2

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8 January 2020

Benjamin T Vroman

3

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8 January 2020

David Loegering

4

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8 January 2020

Larry M Karnitz

6

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8 January 2020

language of work or name

English

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publication date

7 February 2005

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Journal of Biological Chemistry

8 January 2020

published in

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8 January 2020

volume

280

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8 January 2020

issue

14

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8 January 2020

page(s)

14349-14355

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The DNA damage response: putting checkpoints in perspective

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The many substrates and functions of ATM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

A unified view of the DNA-damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Molecular biology. Untangling checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Structural basis for Chk1 inhibition by UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Rad9 protects cells from topoisomerase poison-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The current status of camptothecin analogues as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

ATR Regulates Fragile Site Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Chk1 in the DNA damage response: conserved roles from yeasts to mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Heat shock protein 90 as a molecular target for cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

Reutilization of Immunoblots after Chemiluminescent Detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411890200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411890200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699047%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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