Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. (Q36547655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23267012%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling (English)

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21 February 2020

1

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21 February 2020

Teresa D'Altri

3

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21 February 2020

Stuart Fraser

4

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21 February 2020

Anna Bigas Salvans

11

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21 February 2020

author name string

Ritsuko Shimizu

2

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21 February 2020

Jun Hatakeyama

5

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21 February 2020

Emery H Bresnick

6

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21 February 2020

Ryoichiro Kageyama

7

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21 February 2020

Elaine Dzierzak

8

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21 February 2020

Masayuki Yamamoto

9

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21 February 2020

Lluis Espinosa

10

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21 February 2020

language of work or name

English

0 references

publication date

24 December 2012

1 reference

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Journal of Experimental Medicine

21 February 2020

published in

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21 February 2020

volume

210

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21 February 2020

issue

1

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21 February 2020

page(s)

71-84

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The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

21 February 2020

cites work

1 reference

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The Notch pathway in the developing hematopoietic system

30 September 2017

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Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate

30 September 2017

1 reference

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Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo.

30 September 2017

1 reference

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The canonical Notch signaling pathway: unfolding the activation mechanism

30 September 2017

1 reference

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Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

30 September 2017

1 reference

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High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle

30 September 2017

1 reference

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Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline

30 September 2017

1 reference

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Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

30 September 2017

1 reference

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Of lineage and legacy: the development of mammalian hematopoietic stem cells

30 September 2017

1 reference

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Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.

30 September 2017

1 reference

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The notch pathway positively regulates programmed cell death during erythroid differentiation.

30 September 2017

1 reference

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The Hes gene family: repressors and oscillators that orchestrate embryogenesis

30 September 2017

1 reference

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Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Hematopoietic stem cell fate is established by the Notch-Runx pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Structure and function of the feed-forward loop network motif

30 September 2017

1 reference

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HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

The bHLH gene Hes1 is essential for expansion of early T cell precursors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

30 September 2017

1 reference

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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

30 September 2017

1 reference

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Alternative promoters regulate transcription of the mouse GATA-2 gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

An early haematopoietic defect in mice lacking the transcription factor GATA-2

30 September 2017

1 reference

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Transcription factor GATA-2 is expressed in erythroid, early myeloid, and CD34+ human leukemia-derived cell lines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Direct response to Notch activation: signaling crosstalk and incoherent logic.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549704

Definitive hematopoiesis is autonomously initiated by the AGM region

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23267012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20120993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23267012%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23267012%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

23267012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23267012%20AND%20SRC:MED&resulttype=core&format=json