A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 (Q36549183)

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9 January 2020

title

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 (English)

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9 January 2020

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5

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9 January 2020

author name string

Klaus Piontek

1

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9 January 2020

Luis F Menezes

2

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9 January 2020

Miguel A Garcia-Gonzalez

3

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9 January 2020

David L Huso

4

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9 January 2020

language of work or name

English

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publication date

28 October 2007

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9 January 2020

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9 January 2020

volume

13

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9 January 2020

issue

12

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9 January 2020

page(s)

1490-1495

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describes a project that uses

9 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2302790/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm1675

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cites work

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

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Haploinsufficiency of Pkd2 is associated with increased tubular cell proliferation and interstitial fibrosis in two murine Pkd2 models.

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The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

30 September 2017

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

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Autosomal dominant polycystic kidney disease (ADPKD, MIM 173900, PKD1 and PKD2 genes, protein products known as polycystin-1 and polycystin-2).

30 September 2017

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

30 September 2017

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Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

30 September 2017

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Injury and development in polycystic kidney disease

30 September 2017

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Apoptosis and loss of renal tissue in polycystic kidney diseases

30 September 2017

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Diagnosis of autosomal dominant polycystic kidney disease in utero and in the young infant

30 September 2017

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Hereditary polycystic kidney disease (adult form): a microdissection study of two cases at an early stage of the disease

30 September 2017

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Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

30 September 2017

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Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.

21 September 2018

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Defective planar cell polarity in polycystic kidney disease

21 September 2018

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Evaluation of Cell Proliferation in Rat Tissues with BrdU, PCNA, Ki-67(MIB-5) Immunohistochemistry and In Situ Hybridization for Histone mRNA

21 September 2018

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Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability

21 September 2018

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Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD).

21 September 2018

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Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease

21 September 2018

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12 December 2020

A microdissection study of cystic disease of the kidneys in adults

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12 December 2020

Cyst formation and growth in autosomal dominant polycystic kidney disease

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12 December 2020

Proliferative activity of cyst epithelium in human renal cystic diseases

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12 December 2020

Somatic inactivation of Pkd2 results in polycystic kidney disease

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12 December 2020

PATHOGENESIS OF POLYCYSTIC KIDNEYS. HISTORICAL SURVEY

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12 December 2020

A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo

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12 December 2020

Identifiers

DOI

10.1038/NM1675

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17965720%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17965720%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference