Complement deficiencies in humans and animals: links to autoimmunity (Q36572977)

15 August 2017

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title

Complement deficiencies in humans and animals: links to autoimmunity (English)

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15 August 2017

2

Botto M

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author name string

Lewis MJ

series ordinal

1

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PubMed ID

16923536

15 August 2017

Botto M

series ordinal

2

1 reference

15 August 2017

1 August 2006

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15 August 2017

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15 August 2017

39

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15 August 2017

5

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15 August 2017

367-378

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The localization of in vivo bound complement in tissue section

15 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Immunologic factors and clinical activity in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Systemic lupus erythematosus, complement deficiency, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Molecular basis of a selective C1s deficiency associated with early onset multiple autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Complete complement components C4A and C4B deficiencies in human kidney diseases and systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Inherited deficiency of the second component of complement. Rheumatic disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Hereditary deficiency of the second component of complement (C'2) in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Hereditary dysfunction of the third component of complement associated with a systemic lupus erythematosus-like syndrome and meningococcal meningitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Hereditary deficiency of C3 in animals and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Molecular, genetic and epidemiologic studies on selective complete C1q deficiency in Turkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

A revised estimate of twin concordance in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Genetic sophistication of human complement components C4A and C4B and RP-C4-CYP21-TNX (RCCX) modules in the major histocompatibility complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Identification of a novel family of human endogenous retroviruses and characterization of one family member, HERV-K(C4), located in the complement C4 gene cluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The endogenous retroviral insertion in the human complement C4 gene modulates the expression of homologous genes by antisense inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Diversity in intrinsic strengths of the human complement system: serum C4 protein concentrations correlate with C4 gene size and polygenic variations, hemolytic activities, and body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The intricate role of complement component C4 in human systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Mannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Lupus erythematosus associated with C1 inhibitor deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Acquired C1-inhibitor deficiency in a patient with systemic lupus erythematosus: a case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Serum IgG antibodies to C1q in hypocomplementemic urticarial vasculitis syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Circulating immune complexes in the serum in systemic lupus erythematosus and in carriers of hepatitis B antigen. Quantitation by binding to radiolabeled C1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Autoantibodies to the collagenous region of C1q occur in three strains of lupus-prone mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Autoreactivity to mouse C1q in a murine model of SLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The role of complement in the development of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

C1q deficiency and autoimmunity: the effects of genetic background on disease expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The role of complement and its receptor in the elimination of immune complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Inherited deficiency of erythrocyte complement receptor type 1 does not cause susceptibility to systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Erythrocyte complement receptor type 1, immune complexes, and the rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Complement deficiency and immune complex disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Lupus, DNase and defective disposal of cellular debris

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Novel packages of viral and self-antigens are generated during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Lipid polymorphism and the functional roles of lipids in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Systemic exposure to irradiated apoptotic cells induces autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Requirement of dying cells and environmental adjuvants for the induction of autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Complement-dependent clearance of apoptotic cells by human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophagesin vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Features of systemic lupus erythematosus in Dnase1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

A blast from the past: clearance of apoptotic cells regulates immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Autoimmunity through cytokine-induced dendritic cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

A protective role for innate immunity in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

In vivo studies in C4-deficient guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

The role of complement and complement receptors in induction and regulation of immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Role of complement in induction of antibody production in vivo. Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus. Correlation with serum antinucleosome antibody titers and absence of clear association with disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

Immunosuppressive effects of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930600739233

10.1080/08916930600739233

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16923536