Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome (Q36577092)

15 August 2017

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title

Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome (English)

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15 August 2017

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1

Takahiko Nakagawa

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15 August 2017

2

Katherine R Tuttle

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15 August 2017

Robert A Short

3

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PubMed ID

16932373

15 August 2017

Richard J Johnson

series ordinal

4

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15 August 2017

1 December 2005

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Nature Clinical Practice Nephrology

15 August 2017

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15 August 2017

1

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15 August 2017

80-86

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15 August 2017

2

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Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence

15 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Obesity and the metabolic syndrome in children and adolescents

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Uric acid, evolution and primitive cultures

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Prevalence of attempting weight loss and strategies for controlling weight.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

A randomized trial of a low-carbohydrate diet for obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Metabolic effects of dietary fructose

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Description of the long-term lipogenic effects of dietary carbohydrates in male Fischer 344 rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Insulin stimulation of hepatic triacylglycerol secretion and the etiology of insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Fructose-induced hyperuricaemia

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Effect of oral fructose on urate production

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Fructose-induced hyperuricaemia

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Studies on the mechanism of fructose-induced hyperuricemia in man.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Hyperuricemia induces endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Chronic systemic inflammation in overweight and obese adults.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Allopurinol Normalizes Endothelial Dysfunction in Type 2 Diabetics With Mild Hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Allopurinol improves endothelial dysfunction in chronic heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Nitric oxide release accounts for insulin's vascular effects in humans

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Effect of increased serum urate levels on virgin rats with no arteriosclerosis versus breeder rats with preexistent arteriosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Allantoxanamide-induced myocardial necrosis in Sprague-Dawley vs spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Resurrection of uric acid as a causal risk factor in essential hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Serum uric acid and risk for development of hypertension and impaired fasting glucose or Type II diabetes in Japanese male office workers

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Uric acid concentration in subjects at risk of type 2 diabetes mellitus: relationship to components of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsia.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Hyperuricemia and gout

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Metabolic outcome during 1 year in newly detected hypertensives: results of the Antihypertensive Treatment and Lipid Profile in a North of Sweden Efficacy Evaluation (ALPINE study).

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Mechanisms of endothelial dysfunction in the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Epidemiology of gout and hyperuricemia. A long-term population study

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

THE DISTRIBUTION OF SERUM URIC ACID VALUES IN A POPULATION UNSELECTED AS TO GOUT OR HYPERURICEMIA: TECUMSEH, MICHIGAN 1959-1960

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Trends in serum uric acid levels 1961--1980

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Relation of serum uric acid to mortality and ischemic heart disease. The NHANES I Epidemiologic Follow-up Study

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Uric acid levels in southern Germany in 1989. A comparison with studies from 1962, 1971, and 1984.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

1 reference

7 January 2021

Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: demographic, physical, dietary and biochemical characteristics

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Purine-rich foods, dairy and protein intake, and the risk of gout in men.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Uric acid and diet--insights into the epidemic of cardiovascular disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Plasma uric acid level and its association with diabetes mellitus and some biologic parameters in a biracial population of Fiji

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Hypouricemia and hyperuricemia in type 2 diabetes: two different phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

A role for uric acid in the progression of renal disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide. Role in the vascular and renal complications of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Ramipril and the development of diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Metabolic effects of fructose as a natural sweetener in the physiologic meals of ambulatory obese patients with type II diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Hyperuricaemia, gout, and diabetic abnormality in Polynesian people.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Hyperuricaemia does not impair cardiovascular function in healthy adults

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Beneficial effects of weight loss associated with moderate calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0019

7 January 2021

Identifiers

DOI

10.1038/NCPNEPH0019

1 reference

release_pepqop7s3nefza2nvnnycueqyy

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pepqop7s3nefza2nvnnycueqyy

24 November 2022

mapped directly with Wikidata item

PubMed ID

16932373

1 reference

PubMed ID

16932373