Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway (Q36578703)

15 August 2017

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway (English)

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15 August 2017

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Ulkan Kilic

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15 August 2017

Ertugrul Kilic

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15 August 2017

Zeynep Tuzcu

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15 August 2017

Mehmet Tuzcu

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15 August 2017

Ibrahim H Ozercan

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15 August 2017

Okkes Yilmaz

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15 August 2017

Fikrettin Sahin

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15 August 2017

Kazim Sahin

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15 August 2017

12 January 2013

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15 August 2017

Nutrition and Metabolism

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15 August 2017

10

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15 August 2017

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https://scigraph.springernature.com/pub.10.1186/1743-7075-10-7

15 August 2017

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9 September 2017

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Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury

9 September 2017

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9 September 2017

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9 September 2017

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30 some years of heme oxygenase: from a "molecular wrecking ball" to a "mesmerizing" trigger of cellular events

9 September 2017

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Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt.

9 September 2017

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When melatonin gets on your nerves: its beneficial actions in experimental models of stroke

9 September 2017

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Prophylactic use of melatonin protects against focal cerebral ischemia in mice: role of endothelin converting enzyme-1.

9 September 2017

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Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator

9 September 2017

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9 September 2017

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NF-kappaB regulation in the immune system

9 September 2017

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

9 September 2017

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Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

9 September 2017

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9 September 2017

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Actions of melatonin in the reduction of oxidative stress. A review

9 September 2017

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Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs

9 September 2017

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Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant

9 September 2017

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9 September 2017

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Yersinia enterocolitica isolates of differing biotypes from humans and animals are adherent, invasive and persist in macrophages, but differ in cytokine secretion profiles in vitro

9 September 2017

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TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

30 September 2017

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Manganese superoxide dismutase attenuates Cisplatin-induced renal injury: importance of superoxide.

30 September 2017

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Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells

30 September 2017

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Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite.

30 September 2017

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Newer insights into cisplatin nephrotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Long-term effects of chemotherapy in patients with testicular cancer

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin reduces cardiac inflammatory injury induced by acute exercise

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin, a potent regulator of hemeoxygenase-1, reduces cardiopulmonary bypass-induced renal damage in rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Protective effects of capsaicin against cisplatin-induced nephrotoxicity in rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Nrf2, a multi-organ protector?

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Association between genetic polymorphisms of CYP1A2, arylamine N-acetyltransferase 1 and 2 and susceptibility to cholangiocarcinoma.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Oxidative damage to catalase induced by peroxyl radicals: functional protection by melatonin and other antioxidants

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Role of exogenous melatonin in reducing the nephrotoxic effect of daunorubicin and doxorubicin in the rat.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Pretreatment with melatonin reduces volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin protects against gentamicin-induced nephrotoxicity in rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Structure, Recognition, and Processing of Cisplatin-DNA Adducts.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Melatonin, a pineal secretory product with antioxidant properties, protects against cisplatin-induced nephrotoxicity in rats.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561216

Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria

20 September 2018

1 reference

12 December 2020

Renoprotective effect of Hemidesmus indicus, a herbal drug used in gentamicin-induced renal toxicity

1 reference

12 December 2020

Melatonin attenuates acute renal failure and oxidative stress induced by mercuric chloride in rats

1 reference

12 December 2020

Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades

1 reference

12 December 2020

Role of vascular congestion in cisplatin-induced acute renal failure in the rat

1 reference

12 December 2020

Cisplatin nephrotoxicity

1 reference

12 December 2020

Identifiers

DOI

10.1186/1743-7075-10-7

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference

15 August 2017

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